The subject of Tumour-Associated Macrophages is of interest in the cancer research community, and this book promises to be among the first to discuss a definitive theory on the role of macrophage in tumor development. Among the first books to collectively discuss a definitive theory on the role of macrophage in tumor development. The book appeals to basic scientist working in immunology tumor biology and to some extent pharmacology and biochemistry, clinicians involved in preclinical tumor biology research. Research and intensive discussion of Ik-B and NF-kB. INDICE: Preface. Macrophage Phenotype in Tumors. Role of Tumour-AssociatedMacrophages in the Regulation of Tumour Angiogenesis. The Role of Tumor-Associated Macrophages in Malignant Invasion. Tumor-Induced Immune Suppression by Myeloid Cells. TAM: A Moving Clinical Target. Arginine Metanolism and Tumour Associated Macrophages. Indoleamine 2,3-dioxygenaseAmino acid metabolism and tumor-associated macrophages: regulation in cancer-associated inflammation and immune escape. Vascular Endothelial Growth Factor and Tumor-associated macrophages. TLR Signaling and Tumor-associated Macrophages. SHIP and Tumor-Associated Macrophages. NF-KappaB-Mediated Regulation of Tumor-Associated Macrophages: Mechanisms and Signifance. Role of hypoxia-inducible transcription factors HIF-afor TAM function. Index.
- ISBN: 978-1-4614-0661-7
- Editorial: Springer New York
- Encuadernacion: Cartoné
- Páginas: 145
- Fecha Publicación: 28/11/2011
- Nº Volúmenes: 1
- Idioma: Inglés