Ischemia and loss of vascular autoregulation in ocular and cerebral diseases: a new perspective

From the introduction: “The purpose of the present book is to bring together in a coherent manner new knowledge gained from research over the past 50 yearson the physiology of intraocular pressure, ocular blood flow and the relationof these fundamental parameters to early diagnosis and therapy of vascular diseases of the eye and brain. It will be evident to the reader that the presentation is influenced significantly by the author’s own research. My justification is that by good fortune I have spent many years with superb collaboration helping solve outstanding problems of ocular physiology. This knowledge has increased understanding of the parameters underlying the onset of ischemia and the loss of autoregulation associated with common ocular disease and thereby ledto new methods of diagnosis and therapy.” Decisive guidance on the practical aspects for early diagnosis and treatment of ocular and cerebral diseases for clinicians in ophthalmology, neurology, medicine, optometry and geriatrics Brings together 50 years of research on the physiology of intraocular pressure, ocular blood flow and their relation to early diagnosis and therapy of vasculardiseases of the eye and brain INDICE: From the contents “In vivo” manometric measurements of the steady state Intraocular pressure and the IOP pulse in animals and man.- The rate of formation of the aqueous humor.- The steady state IOP/flow relations in dead and living animal and human eyes.- Homeostasis, autoregulation and relative ischemia.- The pressure/volume relation in eyes of dead and living animal and human eyes.- The ocular perfusion pressure and its influence on the IOP pulse.- Direct and indirect measurements of ocular blood flow in anesthetized and conscious animals and humans.- The morphology and hydrodynamics of the chamber angle.- The sympathetic nerve innervation of the eye and the actions of the adrenergic transmitter norepinephrine on IOP and ocular blood flow.- Manometric studies on the IOP and the vascular circulation in ophthalmic disease.- Indirect measurements of the IOP and the IOP pulse.- The effect of posture and corneal thickness on the IOP.- The Langham analogue and digitized pneumatic tonometers.

• ISBN: 978-0-387-09715-2
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 265
• Fecha Publicación: 01/04/2009
• Nº Volúmenes: 1
• Idioma: Inglés