This
volume focuses on defining the unique attributes of using the zebrafish cancer
model for discovering important pathways and potential drug targets for the
treatment of human cancers. Using the zebrafish model, the volume
explores oncogene and tumor suppressor discovery, chemical genetic approaches,
genomics, epigenetics, cancer imaging, and cell transplantation. Contributed
chapters come from the most prominent laboratories working in this field, which
provides a unique perspective on zebrafish models from a wide spectrum of the
research community. In addition, the book offers a detailed analysis of the most
current research in the area for specific zebrafish cancer models, including T
cell leukemia, rhabdomyosarcoma, liver and pancreatic cancer, melanoma,
neuroblastoma, germ cell tumors, and malignant peripheral sheath tumors. A
chapter is also dedicated to the development and utilization of other piscine
models of cancer. The compilation of chapters in the volume culminates into a
comprehensive and definitive text on zebrafish and cancer, providing a much
needed resource on the powerful attributes of the zebrafish model system.
- ISBN: 978-3-319-30652-0
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 568
- Fecha Publicación: 20/04/2016
- Nº Volúmenes: 1
- Idioma: Inglés