Nutrigenomics and Proteomics in Health and Disease: Towards a systems-level understanding of gene-diet interactions

Now in a revised second edition, Nutrigenomics and Proteomics in Health and Disease brings together the very latest science based upon nutrigenomics and proteomics in food and health. Coverage includes many important nutraceuticals and their impact on gene interaction and health. Authored by an international team of multidisciplinary researchers, this book acquaints food and nutrition professionals with these new fields of nutrition research and conveys the state of the science to date. Thoroughly updated to reflect the most current developments in the field, the second edition includes six new chapters covering gut health and the personal microbiome; gut microbe–derived bioactive metabolites; proteomics and peptidomics in nutrition; gene selection for nutrigenomic studies; gene–nutrient network analysis, and nutrigenomics to nutritional systems biology. An additional five chapters have also been significantly remodelled. The new text includes a rethinking of in vitro and in vivo models with regard to their translatability into human phenotypes, and normative science methods and approaches have been complemented by more comprehensive systems biology–based investigations, deploying a multitude of omic platforms in an integrated fashion. Innovative tools and methods for statistical treatment and biological network analysis are also now included. INDICE: List of Contributors .Preface .SECTION I GENES, PROTEINS AND NUTRITION .1. Personalized Nutrition Lydia Afman .2. Genetic–Epigenetic Interactions Rima Rozen .3. Epigenetics and Metabolic Programming Keith Godfrey and Peter Gluckman .SECTION II BIOACTIVES AND PHYTONUTRIENTS .4. Bioactive Interactions in Food and Natural Extracts Sofia Moço and Denis Barron .5. Bioflavonoids and Biomarkers of Metabolic Syndrome Mary Ann Lila and David H. Murdock .6. Dietary Antioxidants and Bioflavonoids in Atherogenesis and Angiogenesis Mohsen Meydani, Angelo Azzi and Taiki Miyazawa .7. Proteomic and Genomic Approaches to Identify Sensitive Resveratrol Targets César López–Camarillo .8. Genomic Effects of Food Bioactives in Neuroprotection Ashraf Virmani .9. Food–based RNAs and their Bioactivity Kendal Hirschi and Lisa Farmer .SECTION III PREBIOTICS, PROBIOTICS, SYNBIOTICS AND THE GUT ECOSYSTEM .10. Gut Health and the Personal Microbiome Willem de Vos .11. Infant Nutrition and the Microbiome: Systems Biology Approaches to Host–Microbe Interactions Mei Wang and Sharon M. Donovan .12. Gut Microbe–Derived Bioactive Metabolites François–Pierre Martin .SECTION IV NUTRIGENOMIC AND PROTEOMIC TECHNOLOGIES .13. Network Analysis in Systems Nutrition Corrado Priami and Marie–Pier Scott–Boyer .14. Gene Selection for Nutrigenomic Studies Damien Valour .Index

• ISBN: 978-1-119-09883-6
• Editorial: Wiley–Blackwell
• Encuadernacion: Cartoné
• Páginas: 344
• Fecha Publicación: 02/05/2017
• Nº Volúmenes: 1
• Idioma: Inglés