NanoArmored Enzymes for High Temperature Biocatalysis
Kumar, Challa Vijaya
Kasi, Rajeswari M.
NanoArmored Enzymes for High Temperature Biocatalysis provides insight on the central theme of entropy minimization for the stabilization of enzymes using linear synthetic polymers. The book describes methods for the conversion of ordinary enzymes into those that can withstand organic solvents, extreme pHs as well as higher temperatures. Previously many books have been written with the general idea of enzyme stabilization by a variety of hit-or-miss approaches, but emphasis on rational approaches based on 'Molecular Engineering' was never explored. This book addresses missing links in the field of enzyme catalysis at high temperature by exploiting polymer encapsulation of enzyme based on a solid foundation of physical chemistry principles. Provides detailed explanations of the significance of enzymes in industry and academiaExplains the limitation of enzymes under non-ambient and challenging conditionsIncludes synthesis of molecularly-engineered enzyme-polymer nanogelsIncludes applications of enzyme-polymer nanogels in biofuel cells and sensing applicationsSummarizes how the molecular engineering strategy led to solving critical problems in industrial biocatalysis INDICE: 1. Enzymes and their uses 2. Utility of enzymes for biocatalysis 3. Enzyme stabilization problem 4. Conventional enzyme-polymer conjugates 5. Synthesis of enzyme-polymer conjugates via 'Molecular Engineering' 6. Synthesis of bi-enzyme-polymer conjugates 7. Modification of the polymer-armor for catalysis in organic solvents 8. Synthesis of multi enzyme-polymer conjugates 9. Synthesis of graphene-enzyme-polymer conjugates 10. Biocatalysis with NanoArmored enzymes under harsh conditions 11. Advantages and disadvatages of NanoArmored Enzymes 12. Conclusions and future directions of NaoArmoring of Enzymes
- ISBN: 978-0-12-814535-7
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 230
- Fecha Publicación: 01/03/2018
- Nº Volúmenes: 1
- Idioma: Inglés