The Human Microbiome in Early Life, Implications to Health and Disease

The Human Microbiome in Early Life, Implications to Health and Disease presents recent research advances that have highlighted the significance of early life, possibly beginning before birth, in the establishment of both the microbiome and its role in health and disease. The book reviews current knowledge on the origins of the human microbiota in early life, presents exposures which may disturb normal microbial colonization, and covers their implications to the risk of disease. Finally, emerging means to modify the early human microbiome to improve health are discussed. Examines the timeline of the human microbiome, from before conception to infancy, with an emphasis on clinical implicationsEvaluates the effort to understand not only the composition but also the origin of the microbiomeProves the emerging means to modify the human microbiome and particularly 'the first 1000 days of life' improve human health and prevent diseaseGenerates resources to facilitate characterization of the human microbiota to further our understanding of how the microbiome impacts human health and disease INDICE: Section I: Methods to study the microbiome Section II: Pregnancy and fetal life 1. Microbiome during healthy pregnancy 2. Microbiome and complications of pregnancy 3. Microbial signatures of preterm birth 4. Prenatal origins of the infant gut microbiome Section III: Birth - entering the world dominated by microbes 1. Mode of delivery, the infant microbiome and risk of disease 2. Intrapartum and neonatal antibiotic exposure 3. Preterm infants - gut microbiome and complications of prematurity Section IV: Infancy - establishment of the microbiome and healthy development 1. The compositional development of the microbiome in early life 2. Microbes and human milk 3. The early gut microbiome and the risk of chronic disease 4. Antibiotic exposure, the gut microbiome and disease Section V: Modifying early microbial contact 1. Probiotics 2. Prebiotics 3. Clinical data from prenatal interventions 4. Clinical data from postnatal interventions

• ISBN: 978-0-12-818097-6
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 212
• Fecha Publicación: 01/08/2020
• Nº Volúmenes: 1
• Idioma: Inglés