This book is based upon cutting-edge research conducted in the author¿s lab (Cellular Bioengineering), which over the past decade has developed a number ofsophisticated techniques to facilitate use of 3D cell based assays or biosensors. This book uses data from peer-reviewed publications to conclusively justify use of 3D cell cultures in cell-based biosensors (assays) for (HTS). The majority of assays performed in accelerated drug discovery processes are biochemical in nature, but there is a growing demand for live cell-based assays. Unlike biochemical ones, cellular assays are functional approximations of in vivo biological conditions and can provide more biologically relevant information.
- ISBN: 978-1-4200-7349-2
- Editorial: CRC Press
- Encuadernacion: Cartoné
- Páginas: 416
- Fecha Publicación: 25/01/2010
- Nº Volúmenes: 1
- Idioma: Inglés