Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat SARS-CoV-2

Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2. In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization. Deals with biosensors-based approaches that could be exploited to design and develop high throughput, rapid and cost-effective diagnostics technologies for the early detection of viral infections Illustrates the development of multiplexed, miniaturized analytical systems for point-of-care applications Provides information about fabrication protocols for various biosensor based diagnostic approaches that could be directly implemented to develop a novel biosensor Includes the past, present and future status of biosensors, along with information about biosensors currently under clinical trials INDICE: 1. Emergence of coronavirus epidemic and pandemic 2. Emergence of novel coronavirus (SARS-COV-2) and global public health response 3. Lessons learned from coronavirus (SARS-CoV, MERS-CoV and SARS-CoV2) and Socio-economic impact of (SARS-COV-2) pandemic 4. Current therapeutics for COVID-19 management 5. Exploring SARS-COV-2 genomic profiling and strain variation 6. Profiling and pathogenesis of SARS-CoV2 7. Nano-enabled advancements in COVID-19 management 8. Challenges in SARS-CoV2 detection needed to management COVID-19 pandemic 9. State-of-the-art diagnostic to manage coronavirus epidemic and pandemic 10. Biomarkers and risk factors associated with coronavirus infection 11. Protein Biomarkers 12. Genomic Biomarkers 13. Patients fluid as antibody 14. Biological/Synthetic Receptors used for Biosensors development for coronavirus detection (a) Antibody based (b) Enzyme based (c) Aptamer based 15. Electrochemical biosensors for viral infection diagnostics 16. Optical Biosensors for viral infection diagnostics 17. Calorimetric Biosensors for viral infection diagnostics 18. Role of Magnetic nanoparticles in development of Biosensors for viral infection diagnostics 19. Advances in nanomaterials for biosensor development for virus detection 20. Multiplexed biosensors for virus detection 21. Acoustic/electrical biosensors for diagnostic approaches 22. Role of mechanical biosensors in diagnostic approaches 23. Fluorescence Based Biosensors for coronavirus infection diagnostics 24. Raman based biosensors for coronavirus infection diagnostics 25. Miniaturized analytical system for Point-of-care coronavirus infection diagnostics 26. Microfluidic Device with Integrated Biosensors for coronavirus infection diagnostics 27. Currently available Biosensor based approaches for SARS-CoV-2 detection 28. Biosensors based approaches for other viral infection detection 29. Lab-on-chip devices for coronavirus infection diagnostics 30. Scaling up of biosensors for clinical applications and commercialization 31. Future aspects of biosensor-based devices in disease detection

• ISBN: 978-0-12-824494-4
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 476
• Fecha Publicación: 09/03/2022
• Nº Volúmenes: 1
• Idioma: Inglés