Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery

Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery is a comprehensive guide to PLGA nanoparticles for targeting various diseases, covering principles, formation, characterization, applications, regulations and the latest advances. Sections introduce the fundamental aspects of PLGA nanoparticles for drug delivery, including properties, preparation methods, characterization, drug loading methods, and drug release mechanisms, along with a focus on applications. Application of PLGA nanoparticles for the treatment of cancer, inflammatory, cerebral, cardiovascular, and infectious diseases, as well as in regenerative medicine, photodynamic and photothermal therapy, and gene therapy, are all explained in detail. The final chapters explore recent advances and regulatory aspects. This book is a valuable resource for researchers and advanced students across nanomedicine, polymer science, bio-based materials, chemistry, biomedicine, biotechnology, and materials engineering, as well as for industrial scientists and R&D professionals with an interest in nanoparticles for drug delivery, pharmaceutical formulations and regulations, and development of innovative biodegradable materials. Presents the fundamentals of PLGA nanoparticles, including properties, preparation, characterization, and biofate and cellular interactions Provides in-depth coverage of a broad range of specific applications of PLGA nanoparticles across disease treatment, regenerative medicine and therapeutic areas Offers a methodical approach to PLGA nanoparticles in drug delivery that is supported by data tables, illustrative figures and flowcharts INDICE: Part A. Synthesis and characterization of PLGA nanoparticles for drug delivery 1. History, introduction, and properties of PLGA as drug delivery carrier 2. Preparation methods and characterization parameters for nanoparticles 3. Drug loading methods and mechanism of drug release from PLGA nanoparticles 4. Biofate and cellular interactions of PLGA nanoparticles Part B. Application of PLGA nanoparticles in drug delivery 5. Targeting strategies using PLGA nanoparticles for efficient drug delivery 6. PLGA based nanoparticles for treatment of cancer diseases 7. PLGA based nanoparticles for treatment of inflammatory diseases 8. PLGA based nanoparticles for treatment of cerebral diseases 9. PLGA based nanoparticles for treatment of cardiovascular diseases 10. PLGA based nanoparticles for treatment of infectious diseases 11. PLGA based nanoparticles as regenerative medicine 12. Photodynamic and photothermal therapy using PLGA nanoparticles 13. Gene therapy using PLGA nanoparticles Part C. Recent advances and regulatory aspects in PLGA nanoparticles 14. Hybrid PLGA nanoparticles as advanced drug delivery and theranostics application 15. Clinical translation of PLGA nanoparticles into market 16. Biological toxicity and environmental hazards associated with PLGA nanoparticles 17. Conclusion and future prospective of PLGA nanoparticles

• ISBN: 978-0-323-91215-0
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 500
• Fecha Publicación: 01/03/2023
• Nº Volúmenes: 1
• Idioma: Inglés