Synthesis of Epoxides explores different ways of making epoxides, both old and new, and delves into the growing field of heterocyclic chemistry. It's aimed at people who want a variety of methods and need help figuring out which one suits their specific needs. For students, having all the protocols for making epoxides in one place is handy because sometimes you just want to see all the options for creating a particular compound from a specific starting point. Diazo compounds are important synthetic intermediates in organic synthesis but, because of their unpredictable explosive nature and toxicity, their unique reactivity has not been fully exploited and their employment on large scale is avoided. The synthetic usefulness of diazo compounds cannot be overlooked despite their danger. Because of their ylide and 1,3-dipole nature, the diazo compounds have a unique reactivity. The diazo compounds can be utilized for various different conversions including S-ylide-assisted epoxidation, cyclopropanation, or aziridination reactions. This book describes the new and classic methods for the synthesis of epoxides and covers an important and rapidly growing branch of heterocyclic chemistry. Readers will learn about different methods and want information allowing them to evaluate which method is most suitable in particular cases. Students will be able to find the protocols for the synthesis of epoxides in one place within this book because sometimes we want to see all of the possibilities for synthesizing a particular compound from one particular substrate. Explores different ways of synthesizing epoxidesHighlights the wide use of three-membered heterocyclic epoxides in pharmaceutical industryIncludes centralized, comprehensive protocols for the synthesis of epoxides INDICE: 1. Epoxide synthesis2. Epoxide synthesis from alcohols3. Epoxide synthesis from diazo compounds4. Epoxide synthesis from diols5. Epoxide synthesis from diols using sodium reagents6. Epoxide synthesis from haloalcohols7. Epoxide synthesis from carbonyl compounds-I8. Epoxide synthesis from carbonyl compounds-II9. Epoxide synthesis from carbonyl compounds using sulfur ylides-I10. Epoxide synthesis from carbonyl compounds using sulfur ylides-II11. Epoxide synthesis from carbonyl and halo compounds12. Epoxide synthesis from carbonyl and halo compounds using sulfides
- ISBN: 978-0-443-31600-5
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 300
- Fecha Publicación: 15/11/2024
- Nº Volúmenes: 1
- Idioma: Inglés