Handbook of tuberculosis

Coinciding with the first TB therapies to enter clinical trials in 60 years, in 3 volumes this is the most comprehensive account of the latest developmentsin clinical, therapeutic and basic research into the disease, presented by the most prolific researcher in the field. INDICE: VOLUME 1: MOLECULAR BIOLOGY AND BIOCHEMISTRY Tuberculosis - Molecular Genetics and Biochemistry: Introduction Biochemistry of the Cell Wall Glycolipids and Polyketides of M. tuberculosis Physiology of M. tuberculosis Nutrient Transport Iron Uptake by M. tuberculosis Protein Transport PE and PPE GeneFamily Members in M. tuberculosis Virulence/Persistence Mechanisms of M. tuberculosis Genomics Transcriptomics and Transcriptional Regulation Proteomics ofM. tuberculosis Structure Molecular Mechanisms of Dormancy and Resuscitation M. tuberculosis in the Phagosome Molecular Mechanisms of Drug Resistance of M.tuberculosis Experimental Genetics of M. tuberculosis Molecular Evolution of Mycobacteria VOLUME 2: IMMUNOLOGY AND CELL BIOLOGY Introduction: Immunity to M. tuberculosis and BCG Recognition Receptors and Phagocytosis for M. tuberculosis Transcriptional Response of Macrophages and Dendritic Cells to M. tuberculosis Dendritic Cells and Antigen Presentation Killing Mechanisms of the Host Against M. tuberculosis Manipulation of the Macrophage Response Conventional T Cells and their Antigenic Repertoire Unconventional T Cells Cytokines in Tuberculosis Antibodies in Tuberculosis Pathology Maintenance of Latent Infection with Correlates of Protective Immunity Genetics of Resistance (mouse and man) HIV/TB Interactions Novel Vaccination Strategies Against Tuberculosis Experimental Animal Models of Tuberculosis VOLUME 3: CLINICS DIAGNOSTICS THERAPY AND EPIDEMIOLOGY Clinics Diagnostics Therapy Epidemiology: Introduction Global Epidemiology of Tuberculosis Surveillance Studies and Interpretation Molecular Epidemiology of M. tuberculosis Diagnosis of M. tuberculosis: Clinical Clinical Disease (with and without HIV) Management of Tuberculosis Patients Chemotherapy New Drugs and Clinical Drug Trials Latency Drug Resistance in Clinical ContextNovel Drug Treatment Strategies - Co-infections Modeling BCG Vaccination

• ISBN: 978-3-527-31683-0
• Editorial: Verlag Chemie
• Encuadernacion: Cartoné
• Páginas: 1350
• Fecha Publicación: 13/02/2008
• Nº Volúmenes: 3
• Idioma: Inglés