Biomaterials for Precision Cancer Medicine

Biomaterials for Precision Cancer Medicine bridges the gap between materials science and medicine, providing insights into novel biomaterial-based treatments for cancer. The book describes the various smart biomaterial-based treatments available, reviewing how they can be designed to target specific tumor types, adapt to changes in the cell microenvironment and offer smart, personalized therapy for different cancer variants, especially those which are drug-resistant. The book provides a materials-focused look at precision cancer medicine, and is thus useful to materials scientists, biomedical engineers, and biomedical scientists - including cancer and genetic specialists - with an interest in alternative cancer therapies. Reviews the state-of-the-art in precision and translational medicine, setting the scene for the introduction of alternative biomaterial-based therapies Covers a range of biomaterials for personalized cancer treatment, including polymer-protein conjugates, smart nanoparticles, metal compounds, and more Addresses preclinical assessment, health risks, challenges and future perspective of precision anti-cancer biomaterials INDICE: 1. Introduction to cancer2. Cancer therapy in the era of precision medicine3. Precision medicine: Aspects in translational medicine4. Biomaterials: Fundamentals, processing, and applications5. Possible targets for biomaterials in cancer treatment6. Biomaterials-based cancer diagnostics: Recent advances7. Anti-cancer biomaterials: A special design for precision medicine8. Natural plant-derived anti-cancer biomaterials9. Combination cancer therapy by bio-macromolecules and small molecules10. Biomaterials for cancer immunotherapy11. Biomaterials for engineering tumor microenvironment12. Biomaterials for cancer targeted drug delivery13. Engineered smart biomaterials for anti-cancer gene delivery‏14. Biofunctionalization of materials for targeting cancer cells15. Reactive oxygen species (ROS)-responsive materials in cancer therapy16. Natural polymers for diagnosis and treatment of cancers17. Synthetic polymers for malignancies treatment18. Polymer-protein and polymer-drug conjugates in cancer therapy19. Magnetic calcium phosphates for imaging and treating of cancers20. Hydroxyapatite nanoparticles as anti-cancer agents21. Bioactive magnetic glass-ceramics for cancer treatment22. Mesoporous glasses in cancer therapy23. Carbon biomaterials for cancer therapy: opportunities and challenges24. Metals and metal compounds for cancer photothermal therapy25. Smart nanoparticles for the treatment of drug-resistant tumors26. Managing malignancies by magnetic electrospun nanofibers27. Multiparametric preclinical assessment of theranostics materials28. Health risk assessment of anti-cancer biomaterials29. Future perspectives and challenges for biomaterials

• ISBN: 978-0-323-85661-4
• Editorial: Woodhead Publishing
• Encuadernacion: Rústica
• Páginas: 790
• Fecha Publicación: 01/10/2024
• Nº Volúmenes: 1
• Idioma: Inglés