Microwaves in organic and medicinal chemistry

Tailored to the needs of medicinal and natural products chemists, the second edition of this unique handbook brings the contents up to speed, almost doubling the amount of chemical information with an additional volume. As in the predecessor, a short introductory section covers the theoretical background and evaluates currently available instrumentation and equipment. The main part of the book then goes on to systematically survey the complete range of published microwave-assisted synthesis methods from their beginnings in the 1990s to mid-2011, drawing on data from more than 5,000 reports and publications. Throughout, the focus is on those reactions, reagents and reaction conditions that work, and that are the most relevant for medicinal and natural products chemistry. A much expanded section is devoted to combinatorial, high-throughput and flow chemistry methods. INDICE: FUNDAMENTALSIntroductionMicrowave TheoryEquipment ReviewMicrowave Processing TechniquesGENERAL ORGANIC SYNTHESISCarbon-carbon bond formationsCarbon-hetero atom bond formationsOther transition metal-mediated processesRearrangement reactionsCycloaddition reactionsOxidationsMulticomponent reactionsRing-opening reactionsAddition and elimination reactionsSubstitution reactionsReductive aminationsProtection/deprotection chemistryHeterocycle synthesisCOMBINATORIAL AND HIGH-THROUGHPUT SYNTHESISSolid-phase organic synthesisSoluble polymer-supported synthesisFluorous phase organic synthesisIonic liquid phase-supported synthesisPolymer-supported reagentsPolymer-supported catalystsPolymer-supported scavengers

• ISBN: 978-3-527-33185-7
• Editorial: Wiley-VCH
• Encuadernacion: Cartoné
• Páginas: 683
• Fecha Publicación: 18/04/2012
• Nº Volúmenes: 1
• Idioma: Inglés