This book presents the latest findings in mechanosensitivity of the nervous system. The nervous system stands out from a number of tissues because besides reacting to the mechanical stress it is transmitting its own response to otherorgans and tissues, which are located downstream of its signaling pathway. For this reason any type of mechanical stimulation of the nervous system, which is capable of triggering a physiological response, has high scientific and practical significance, since it allows its use beyond a particular experimental model anywhere where it is contributing to a particular pathological condition. This book is a unique collection of reviews outlining the current knowledge and the future developments in this rapidly growing field. Currently, investigations of the effects of mechanical stress on the nervous system are focused on several issues. For the first time one volume brings together a comprehensive up-to-date description of mechanosensitive ion channels in the nervous cellsFor the first time one volume provides a throughout review of mechanosensitivity of the receptors, present in the nervous system For the first time it gives a reader a complete overview of biomechanics of the nervous system INDICE: From the contents I Mechanosensitivity of Nervous Cells. 1. Mechanosensitive Channels in Neuronal and Astroglial Cells in the Nervous System. 2.Ion Channels with Mechanosensitivity in the Nervous System. 3. Mechanosensitive Cation Currents and their Molecular Counterparts in Mammalian Sensory Neurons. 4. Neurons and Cell Swelling-Induced Peptide Hormone Secretion. 5. Neuronal Mechanosensitivity in the Gastrointestinal Tract.- II Mechanosensitivity of the Receptors. 6. Mechanosensitivity of the Cochlea. 7. Osmoreceptors in cochlear outer hair cells. 8. Are Stretch-Activated Channels an Ocular Barometer? 9. Neuromodulation of mechanosensory input to the insect CNS.- III Biomechanicsof Nervous System. 10. Biomechanics of the CNS. 11. The neural representationof Kinematics and Dynamics in multiple brain regions: The use of force field reaching paradigms in the Primate and Rat. 12. Mechanical properties of brain tissue: Characterisation and constitutive modelling.
- ISBN: 978-1-4020-8715-8
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 350
- Fecha Publicación: 01/10/2008
- Nº Volúmenes: 1
- Idioma: Inglés