Posttraumatic Epilepsy: Basic and Clinical Aspects

Posttraumatic Epilepsy: Basic and Clinical Aspects provides a synthesized resource on recent basic and clinical science developments in the field of posttraumatic epilepsy. The book provides a clear understanding of the history of studies of posttraumatic epilepsy and the military and civilian data regarding risk of epilepsy after head trauma. It also covers the basic science of animal models of head injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors also explore novel therapeutic approaches to prevent posttraumatic epilepsy. It is written for basic and clinical researchers in neuroscience, as well as clinicians treating patients with epilepsy. Synthesizes studies that demonstrate risk factors for susceptibility to epilepsy after head trauma Reviews animal models of head injury Explores novel therapeutic approaches to prevent posttraumatic epilepsy INDICE: 1. History of posttraumatic epilepsy2. Epidemiology of posttraumatic epilepsy (from military and civilian data sources)3. Neuropathology of posttraumatic epilepsy4. Clinical trials of agents to prevent posttraumatic epilepsy5. Surgical treatment of posttraumatic epilepsy6. Animal models of traumatic brain injury7. Incidence of posttraumatic epilepsy in animal models of traumatic brain injury8. Cellular and molecular changes in animal models of posttraumatic epilepsy9. Blood-brain barrier disruption and posttraumatic epilepsy10. Inflammation and posttraumatic epilepsy11. Treatment trials in animal models to prevent posttraumatic epilepsy12. Therapeutic targets and future directions

• ISBN: 978-0-323-90099-7
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 250
• Fecha Publicación: 01/10/2022
• Nº Volúmenes: 1
• Idioma: Inglés