Marine Specialized (Secondary) Metabolites and their Diverse Applications
Jayawardena, Thilina
Sanjeewa, Asanka
Over the past 50 years, more than 20,000 natural compounds have been identified in the marine environment, with an increasing focus on marine metabolites as potential sources for developing effective therapeutic agents. The field of marine drug discovery has seen remarkable growth in recent years, with numerous marine-derived therapeutic candidates in various stages of clinical trials or awaiting approval. The ocean is a potential source of natural products with diverse pharmacological properties, including antimicrobial, anticancer, antiviral, antioxidative, and anti-inflammatory activities. However, commercializing marine natural products has been challenging due to low yields and specificity of specialized (secondary) metabolites. Marine Specialized (Secondary) Metabolites and their Diverse Applications provides a broad overview of marine specialized metabolites and their potential in various industries. With comprehensive coverage, relevance to current trends, interdisciplinary approach, and practical applications, this book includes specific compounds or organisms, with a particular focus on addressing the challenges and limitations associated with them. Chapters follow a clear structure, presenting a consistent and organized format that makes it easier for readers to navigate the contentTakes an interdisciplinary approach, provides readers with a broad perspective on natural compounds and secondary metabolitesCovers critical and comprehensive literature reviews of the advancements and diverse applications of marine specialized metabolites INDICE: Part I - Chemistry and biochemistry of marine specialized metabolites1. Phenolic compounds and their halogenated derivatives2. Terpenoids3. Alkaloids4. Sterols5. Saccharide derivatives6. PeptidesPart II - Application of marine specialized metabolites7. Marine secondary metabolites; in the long haul fight against cancer8. Marine secondary metabolites in oxidative stress are promising9. Promoting marine specialized metabolites against inflammation10. Marine neutraceuticals; a solution for digestive tract health11. Future prospects of marine resources in fighting diabetics12. Advances and prospects in the field of cosmeceuticals with marine resources13. Marine environment as a wonderful source over viral infections14. Reverse aging is possible with marine resources15. How to implement marine secondary metabolites in obesity struggle16. Antimicrobial properties of marine specialized metabolitesPart III - Marine organisms as a natural product resource and beyond17. Marine secondary metabolites as a natural product resource18. Contributions of marine secondary metabolites to medicinal chemistry19. Blue-bioeconomy; marine specialized metabolites at the forefront20. Marine secondary metabolites; an underexplored subject in metabolomics21. Advances in marine secondary metabolite based metabolmics
- ISBN: 978-0-443-29843-1
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 350
- Fecha Publicación: 01/01/2025
- Nº Volúmenes: 1
- Idioma: Inglés