Tumor-Targeting with Stimuli-Responsive Vesicular Nanocarriers: Basics to Emerging Applications

Tumour-Targeting with Stimuli Responsive Vesicular Nanocarriers: Basics to Emerging Applications not only acquaints scientists and science interns with the fundamental knowledge of the experimental aspects and state-of-the-art technology for vesicular carriers to equip their rational application in tumor targeting, but also provides a holistic understanding of regulatory concerns, patents, and clinical trials. In 15 chapters. this book provides basics and advances in stimuli-responsive vesicular carriers for tumor targeting based on findings outlined in highly organized tables, illustrative figures, and flow charts.With a focus on the extrapolation of bioengineering tools in the domain of vesicular carriers, stimuli-responsive features concerning tumors, drug delivery approaches, and associated challenges, it helps readers to define the major gaps in knowledge that can lead to significant scientific discoveries in therapy, diagnosis, and theragnosis of cancer. Addresses the unmet needs and challenges confronted by nanotechnologists to foster collaboration of biologists, chemists, physicists, bioengineers, and cliniciansProvides an explicit account of vital aspects of PEGylation of these carriers and challenges for effective tumor targetingPresents a need-of-hour discussion over regulatory concerns, clinical trials, and patents INDICE: 1. Anomalous tumour microenvironment: exploitable features for drug delivery2. Vesicular carriers for stimuli-responsive drug delivery to tumours: design considerations3. Role of dePEGylation in vesicular carriers mediated stimuli-responsive drug delivery to tumours4. pH-responsive vesicular carriers as promising tools for tumour targeting5. Enzyme-responsive vesicular carriers as an emerging approach for tumour targeting6. Redox-responsive vesicular carriers for potential tumour-targeting applications7. Hypoxia-responsive vesicular carriers for enhanced tumour targeting8. Magnetically responsive and thermo-responsive vesicular carriers for improved drug delivery to tumours9. Ultrasound-responsive vesicular carriers for tumour targeting10. Light-triggered vesicular carriers for tumour targeting11. Electro- and Mechano-responsive vesicular carriers targeting tumours12. Emerging applications of stimuli-responsive novel vesicular carriers: Exosomes, supramolecular vesicles, and catanionic vesicles13. Vesicular carriers with multipronged features for diagnostics and theranostics14. Nanotoxicity and challenges in stimuli-responsive vesicular carriers targeting tumour15. Patents, clinical trials, and regulatory concerns with stimuli-responsive vesicular carriers.

• ISBN: 978-0-443-29125-8
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 240
• Fecha Publicación: 03/03/2025
• Nº Volúmenes: 1
• Idioma: Inglés