Molecular and translational vascular medicine

Molecular and Translational Vascular Medicine will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of vascular biology and medicine. The text provides new insight into the basic mechanisms of classic vascular pathophysiologic processes like angiogenesis, atherosclerosis, thrombosis, and vasculitis. Furthermore, it covers new areas of investigation including the roleof the ubiquitin proteasome system in vascular disease, endothelial progenitor cells for disease treatment, and the genetic basis of thoracic aortic aneurysms. Lastly, this volume includes sections on the newly emerging field of therapeutic angiogenesis, and the developing technology of nanoparticle-based imaging and therapeutic treatment of the diseased vasculature. All chapters are written by established experts in their fields, including pathologists, cardiologists, cardiovascular surgeons, and general practitioners as well as translational biomedical researchers in a wide range of disciplines. While comprehensive, the material will be presented in a manner that simplifies the complex pathophysiologic mechanisms that underlie common vascular diseases.Molecular and Translational Vascular Medicine will be of great value to a broad audience including pathologists, cardiologists, clinicians treating patients, residents and fellows as well translational biomedical researchers. INDICE: Section 1: Recent advances in understanding and imaging the molecular and genetic basis of vascular diseases. Ch. 1- The Molecular Biology and Genetics of Aneurysms Helena Kuivaniemi Gerard C. Tromp David J. Carey James R. Elmore Ch. 2- The Molecular Biology and Treatment of Systemic Vasculitis in Children Despina Eleftheriou Paul A. Brogan Ch. 3- Recent Insights into the Molecular and Cellular Contributions to Venous Thrombosis Peter K. Henke Jose Antonio Diaz Daniel D. Myers, Jr. Thomas W. Wakefield Ch. 4- The Ubiquitin Proteasome System in Endothelial Cell Dysfunction and Vascular Disease Najeeb A. Shirwany Ming-Hui Zou Ch. 5- Molecular Imaging of Vascular Inflammation, Atherosclerosis, and Thrombosis Dan Jane-wit Mehran M. Sadeghi Section 2: The therapeutic potential of angiogenesis, nanomedicine, and endothelial progenitor cellsin the treatment of vascular disease Ch. 6- Molecular Regulation of Vasculogenesis and Angiogenesis: Recent Advances and Future Directions George E. DavisCh. 7- Therapeutic Angiogenesis for Critical Limb Ischemia: Complex Mechanisms and Future Challenges Yihai Cao Ch. 8- Modulating the proliferative responseto treat restenosis after vascular injury Vicente Andrés García José Javier Fuster Carlos Silvestre Roig Rainer Wessely Ch. 9- Cardiovascular Nanomedicine:Challenges and Opportunities Biana Godin Ye Hu Saverio La Francesca Mauro Ferrari Ch. 10- Endothelial Progenitor Cells in the Treatment of Vascular DiseaseGareth J. Padfield

• ISBN: 978-1-61779-905-1
• Editorial: Humana
• Encuadernacion: Cartoné
• Fecha Publicación: 29/07/2012
• Nº Volúmenes: 1
• Idioma: Inglés