Inflammation and allergy drug design

ÍNDICE: Part I: Cells contributing to the pathogenesis of allergic diseasesin the respiratory tract. Novel anti-inflammatory drugs based on targeting lung dentritic cells and airway apithelial cells (Bart Lambrecht, Hamida Hammad,Monique Willart and Maud Plantinga). 2 Th2 cells (Marsha Wills-Karp). 3 Importance of Th17 and Th1-associated responses for the development of asthma (Yoshimoto Tomohiro, Tsutsui Hiroko, Nakanishi Kenji). 4 Regulatory T cells (Christopher Corrigan, Kimuli Ryanna). 5 A role for invariant NKT cell subsets in thepathogenesis of various allergic disorders (Masaru Taniguchi, Mayumi Tamari, Hiroshi Watarai, Michishige Harada). 6 Regulatory roles of B cells in the Allergy and inflammation (Kiyoshi Takatsu, Masashi Ikutani, and Yoshinori Nagai). 7 Mast cells (Steve Galli, Mindy Tsai). 8 Eosinophils (James Lee, Nancy Lee, Sergei Ochkur, Mark Dahl). 9 Basophils (Don McGlashan). 10 Epithelial cells (Darryl Knight, Tillie-Louise Hackett, Stephanie Warner, Dorota Stefanowicz). 11 Fibroblasts (Alastair Stewart, Lillian Soon, Michael Schuliga). 12 Smooth muscle cells (Andrew Halayko). Part II Cytokines contributing to the pathogenesis of allergic diseases in the respiratory tract. 13 IL-4/IL-13/IL-9 (Kenji Izuhara, Shiochiro Ohta, Hiroshi Shiraishi, Shiochi Suziki). 14 IL-3/IL-5/GM-CSF (Manuel Jordana, Alba Llop-Guevara, Josip Marcinko, Ramzi Fattouh). 15 IL-15, IL-17, and IL-25 (Hiroshi Nakajima, Itsuo Iwamoto). 16 TSLP (Yong-Jun Liu, Kazuhiko Arima). 17. Interleukin-10 (Larry Borish, Whitney W Stevens, John W Steinke). 18 Anti-TNFa strategies in experimental asthma and clinical trials: what have we learned? (Christopher Brightling, Yassine Amrani, Latifa Chachi, Dhan Desai). 19 Profibrotic and Angiogenic Factors in Asthma (Francesca Levi- Schaffer, Neville Berkman). 20 Chemokines (Luis Manuel Teran Juarez, Juan R Velazquez). 21 Epithelial growth factors (Shu Hashimoto, Yaihiro Gon). Part III Other mediators contributing to the pathogenesis of allergic diseases in the respiratory tract. 22 Prostanoids (Maria Belvisi, Deborah Clarke and Sarah Maher). 23Leukotrienes (Mark Peters Golden, Katsuhide Okunishi). 24 Proteases in Allergy (Hirohisa Saito, Keisuke Oboki). 25 Toll-like receptors (Chris Karp, JessicaL. Allen, Aurelien Trompette).

• ISBN: 978-1-4443-3014-4
• Editorial: Wiley-Blackwell
• Encuadernacion: Cartoné
• Páginas: 328
• Fecha Publicación: 26/08/2011
• Nº Volúmenes: 1
• Idioma: Inglés