Congenital Adrenal Hyperplasia: A Comprehensive Guide

Congenital adrenal hyperplasia, also known as 21-hydroxylase deficiency or adrenogenital syndrome, is an inherited disorder of the adrenal glands. It can be difficult to diagnose and treatment needs to be individualized to suit each person. The authors detail a successful treatment which can be done by tailoring the dose of hydrocortisone to suit the patient using 24 hour cortisol and 17 OHP profiles. Congenital Adrenal Hyperplasia addresses how hydrocortisone works, what can go wrong, how to correct it, and explains that the timing of doses is extremely important as is measuring the cortisol attained from a dose. Congenital Adrenal Hyperplasia provides an in-depth analysis of this disorder for pediatric endocrinologists as well as primary care providers to provide affected patients with an updated model of care and appropriate treatment. Patients and family members will benefit from the trend-forward information presented and will be empowered to approach their health care providers with the expectation of receiving individualized care and treatment of the disorder. Outlines the basics of the disease and its interrelation with hormones and bodily functionPresents the known cognitive and emotional aspects of the diseaseOffers an important resource for those physicians who are used to seeing and treating individual symptoms, rather than a disease complexReviews multidisciplinary management as well as post-treatment management of the disease INDICE: 1. Physiology of the Adrenal Gland: How does it Work? 2. How Males and Females Develop 3. Genetics of Congenital Adrenal Hyperplasia 4. Common Forms of Congenital Adrenal Hyperplasia 5. Other Blocks in the Pathway Causing Congenital Adrenal Hyperplasia 6. The Growth Process 7. Hormonal Control of Puberty 8. Biochemical Tests Used for Diagnosis 9. Monitoring Long-Term Outcomes 10. Growth: Over-treatment/Under-Treatment 11. Puberty in Poorly Controlled CAH 12. Weight, Diabetes, Blood Pressure - Hypertension and Hypotension 13. Bone Density and Osteoporosis 14. Fertility 15. Sleep and Mood Alterations 16. Abdominal, Skin, and Other Problems 17. History of Steroid Development 18. Glucocorticoid Treatment 19. Glucose and Cortisol 20. Hydrocortisone 21. Dosing and the Circadian Rhythm 22. Cortisol and 17 Hydroxyprogesterone 23. Using Profiles to Assess Cortisol Replacement 24. Monitoring Hydrocortisone Therapy 25. Other Hormones and Their Role 26. Missing a Dose 27. Intravenous, Intramuscular and other Forms of Hydrocortisone 28. The Pump Method for Achieving a Normal Circadian Cortisol Replacement 29. Stress Dosing for Surgery, Exams, and Exercise 30. Medical Management 31. Prednisolone and Dexamethasone 32. Fludrocortisone 33. Travel and Time Zones 34. Emotional Aspects of Living with CAH

• ISBN: 978-0-12-811483-4
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 421
• Fecha Publicación: 01/04/2017
• Nº Volúmenes: 1
• Idioma: Inglés