Strategies and Tactics in Organic Synthesis, Volume 15, provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. Readers will be educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs and building molecules with atom and step economies that provide functional solutions to create a better world. Provides insight and offers new perspective to problem-solving Presents state-of-the-art developments in organic synthesis Written by leading experts in the field Uses firsthand narrative accounts to vividly illustrate the challenges and joys involved in advancing the science of organic synthesis INDICE: 1. Amaryllidaceae isocarbostyril alkaloids2. Enzymatic dihydroxylation of aromatic compounds: Nature's unique reaction and its impact on the synthesis of natural products3. Intermolecular oxidopyrylium [5+2] cycloaddition chemistry and its application toward the synthesis and study of highly oxygenated troponoids4. Aryne-mediated construction of fluorene skeletons and its applications to total synthesis of selaginpulvilins5. Cycloisomerizations across three states: the total synthesis of gelsenicine6. Tetrapetalones ruminations, trials and tribulations7. The synthesis of herqulines B and C8. First total synthesis of the dimeric naphthoquinonopyranolactone natural product (-)-crisamicin A. how procrastination may be of help in binaphthyl synthesis9. Strategies and discoveries leading to the synthesis of trichoaurantianolide natural products10. 4-exo-dig cyclocarbopalladation, discovery and application in the synthesis of complex polycyclic molecules
- ISBN: 978-0-12-822212-6
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 444
- Fecha Publicación: 15/11/2021
- Nº Volúmenes: 1
- Idioma: Inglés