A classic in the area of organic synthesis, Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, we are given stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project tell of the excitement of conception, the frustration of failure and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This book series shows how synthesis is really done, and we are educated, challenged and inspired by these accounts, which portray the idea that triumphs do not come without challenges. We also learn that we can meet challenges to further advance the science and art of organic synthesis, driving it forward to meet the demands of society, in discovering new reactions, creating new designs and building molecules with atom and step economies that provide solutions through function to create a better world. Presents state-of-the-art developments in organic synthesisProvides insight and offers new perspective to problem-solvingWritten by leading experts in the field INDICE: 1. The Substrate-Directed Heck-Matsuda Arylations. From Curiosity to a Valuable Synthetic Tool, Carlos Duarte Correia 2. (-)-Berkelic Acid: Lessons Learned from our Investigations on Scalable Total Synthesis, Francisco J. Fañanás 3. Replicating Nature's Schemes with Pericyclic Reactions, Kathlyn A. Parker 4. Total Synthesis of Chinensolide B: Overcoming Functional Group Selectivity and a Mislabeled Bottle of Carvone, Dennis Hall 5. The Synthesis of Borrerial and Flindersial Akaloids via Biosynthesis-Inspired Strategies, Jeremy A. May 6. Synthesis of (±)-Amathaspiramide F: Stereochemical Switch of a [2,3]-Stevens Rearrangement, Uttam Krishan Tambar 7. Halocylopropene Furan Cycloadditions: Application to the Total Synthesis of the Frondosins, Dennis Wright 8. Structure Inspires a New Method that Delivers the Synthesis of Natural Products and Analogs in the Pederin Family, Paul Floreancig 9. Gliocladin C: The Development of Visible Light Mediated, Catalytic Intermolecular Pyrroloindoline-indole Radical Coupling Reaction, Corey Stephenson 10. Adventures in Atropselective Synthesis, Jared Shaw 11. Sleepless Nights: The Total Synthesis of the Anticancer Australian Rainforest Polyketide EBC23, Craig McKenzie Williams 12. Total Synthesis of Crinipellin B, Hee-Yoon Lee
- ISBN: 978-0-12-417185-5
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 320
- Fecha Publicación: 01/08/2014
- Nº Volúmenes: 1
- Idioma: Inglés