Ranunculales Medicinal Plants: Biodiversity, Chemodiversity and Pharmacotherapy

Ranunculales is an order of flowering plants belonging to a paraphyletic group known as the basal eudicots. Medicinal plants of this order provide myriad pharmaceutically active components commonly used worldwide in ethnomedicine and traditional Chinese medicine. Interest in plant-based medicinal resources has led to discoveries of many novel compounds in various species, and to investigations on their chemodiversity, biodiversity and pharmacotherapy. Ranunculales Medicinal Plants covers this order of flowering plants comprehensively in this context; detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera, and their relevance to drug efficacy. The book carries out an exhaustive survey of the literature in order to characterize global trends in the application of flexible technologies. The interrelationship between Chinese species and between Chinese and non-Chinese species is inferred, in the text, through molecular phylogeny, based on nuclear and chloroplast DNA sequencing. The title discusses the conflict between chemotaxonomy and molecular phylogeny, in the context of drug discovery and development. It offers invaluable and holistic coverage for the study of Ranunculales as a pharmaceutical resource. Describes current perceptions of biodiversity and chemodiversity of Ranunculales medicinal plantsExplains how the conceptual framework of plant pharmacophylogeny benefits the sustainable exploitation of Ranunculales pharmaceutical resourcesDetails how Ranunculales medicinal plants work from the chemical level upwardCovers how the polypharmacology of Ranunculales compounds might inspire new chemical entity design and development for improved treatment outcome INDICE: 1. Genomics and Evolution in Traditional Medicinal Plants: Road to a Healthier Life2. Mining chemodiversity from biodiversity: pharmacophylogeny of medicinal plants of Ranunculaceae3. Mining chemodiversity from biodiversity: pharmacophylogeny of Ranunculales medicinal plants (except Ranunculaceae)4. Drug metabolism and pharmacokinetic diversity of Ranunculaceae medicinal compounds5. Drug metabolism and disposition diversity of Ranunculales phytometabolites: a systems perspective6. Anticancer Chemodiversity of Ranunculaceae Medicinal Plants: Molecular Mechanisms and Functions7. Biodiversity, chemodiversity and pharmacotherapy of Thalictrum medicinal plants8. Biodiversity, chemodiversity and pharmacotherapy of Anemone medicinal plants9. Biodiversity, chemodiversity and pharmacotherapy of Ranunculus medicinal plants

• ISBN: 978-0-12-814232-5
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 404
• Fecha Publicación: 25/04/2018
• Nº Volúmenes: 1
• Idioma: Inglés