Design and analysis of vaccine studies

Design and analysis of vaccine studies

Halloran, M. Elizabeth
Longini, Ira M.
Struchiner, Claudio J.

80,03 €(IVA inc.)

INDICE: Introduction and examples.- Overview of vaccine effects and study designs.- Immunology and early phase trials.- binomial and stochastic transmission models.- R0 and deterministic models.- Evaluating protective effects of vaccination.- Modes of action and time-varying VES.- Further Evaluation of Protective Effects.- Vaccine effects on post-infection outcomes.- House-hold basedstudies.- Analysis of households in communities.- Analysis of independent households.- Assessing Indirect, total and overall effects.- Randomization and baseline transmission.- Surrogates of protection.

  • ISBN: 978-0-387-40313-7
  • Editorial: Springer
  • Encuadernacion: Cartoné
  • Páginas: 389
  • Fecha Publicación: 01/01/2010
  • Nº Volúmenes: 1
  • Idioma: Inglés