Reproductive and Developmental Toxicology, Second Edition, is a comprehensive and authoritative resource that provides the latest literature on this complex subject with a primary focus on three core components-parent, placenta, and fetus-and the continuous changes that occur in each. Enriched with relevant references describing every aspect of reproductive toxicology, this revised and updated resource addresses the totality of the subject, discussing a broad range of topics, including nanoparticles and radiation, gases and solvents, smoking, alcohol and drug abuse, and metals, amongst others. With a special focus on placental toxicity, this book is the only available reference to connect the three key risk stages, also including discussions on reproductive and developmental toxicity in domestic animals, fish, and wildlife. Completely revised and updated to include the most recent developments in the field, the book is an essential resource for advanced students and researchers in toxicology, as well as biologists, pharmacologists, and teratologists from academia, industry, and regulatory agencies. Provides a complete, up-to-date, integrated source of information on the key risk stages during reproduction and developmentIncludes new chapters covering significant developments, such as dose-response assessment for developmental toxicity, juvenile toxicity, and neural tube defects, as well as emerging science, such as stem cell application, toxicoproteomics, metabolomics, endocrine disruption, surveillance and regulatory considerations, and risk assessmentOffers diverse and unique in vitro and in vivo toxicity models for reproductive and developmental toxicity testing in a user-friendly format that assists in comparative analysis INDICE: Section I: General Section II: Toxicity Testing Models and Safety Evaluation Section III: Nanoparticles and Radiation Section IV: Gases and Solvents Section V: Drugs of Abuse and Addiction, smoking and alcohol Section VI: Pharmaceuticals and Food Additives Section VII: Metals Section VIII: Pesticides, Industrial, and Other Environmental Contaminants Section IX: Phytotoxicants, mycotoxins, and zootoxins Section X: Special Topics Section XI: Endocrine Disruption, Mutagenicity, Carcinogenicity, Infertility and Teratogenicity Section XII: Toxicologic Pathology Section XIII: Placental Toxicity Section XIV: Domestic and Wildlife Species
- ISBN: 978-0-12-804239-7
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 1490
- Fecha Publicación: 01/02/2017
- Nº Volúmenes: 1
- Idioma: Inglés