Neuroimmunology of the skin: basic science to clinical practice

Much anecdotal information has suggested an influence of psychology and the nervous system on immunity within the skin and the expression of inflammatory skin disorders. Recent years have seen an explosion of knowledge providing a scientific basis for important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin. The results of recent investigations have important implications, not only for an understanding of cutaneous immunity, but also for the development of novel treatments fordiseases involving abnormal inflammation or immune reactivity within the skin. This book provides a comprehensive and interdisciplinary review of the molecular biology, cell biology, biochemistry and clinical aspects of nervous system–immune system interactions within the skin. It includes contributions from leading world experts in these areas. The contents are relevant to both investigators and clinicians interested in the skin, its functions and its disorders.Up-to-date, comprehensive and concise book on the important regulatory interactions between the nervous system, the endocrine system and the immune system within the skin Written by leading experts in the world in these areas Highly structured with reader-friendly format (core messages, etc.) Of interest to both researchers and clinicians of various disciplines (dermatologists, neurologists, psychiatrists, etc.) INDICE: Introduction.- Basic Neuroimmunology of the Skin.- Neuroanatomy ofthe Skin.- Neuroreceptors and Mediators.- Interaction of the Neuroimmune and Vascular Systems.- Immune Circuits of the Skin.- Modulation of Immune Cells byProducts of Nerves.- Regulation of Immune Cells by POMC Peptides.- Regulationof Cutaneous Immunity by Catecholamines.- The Role of Neuropeptide Endopeptidases in Cutaneous Immunity.- Toll-Like Receptors: Role in Neurobiology.- Stress in Cutaneous Immunity.- Neuroendocrine Effects of Stress.- Stress and Cutaneous Immunity.- Effects of Stress on Inflammatory Skin Disease.- Photoneuroimmunology: Modulation of the Neuroimmune System by UV-Light.- Neurophysiology of Itch.- Autonomic Effects on the Skin.- Neurobiology of Hair, Sebaceous Glands,Eccrine/Apocrine Glands.- The Nervous System and the Pathophysiology of Skin Disorders.- Psoriasis.- Atopic Dermatitis.- Alopecia Areata.- Urticaria.- AcneVulgaris and Rosacea.- Wound Healing.- Aging.- Index.

• ISBN: 978-3-540-35986-9
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 355
• Fecha Publicación: 01/10/2008
• Nº Volúmenes: 1
• Idioma: Inglés