Nanobiosensors for Biomolecular Targeting

Biosensors combine the component of biological origin and physicochemical detector, in order to showing the presence of analyte in a given sample. The use of bionanotechnology has led to a significant advancement in the progression of nanobiosensor and it has been used effectively for biomedical diagnosis. The generation of high-performance biosensors could be a basic platform for the identification causative agents and subsides the disease spreading through surveillance. Biosensors have already been demonstrated their efficacy in the detection of life-threatening diseases and attested to be an appropriate tool for forecasting emerging diseases. The quality of sensor is determined by its level of sensitivity and specificity, and it is possible with proper substrate selection having fine-tuned hydrophobicity/hydrophilicity can significantly alter the bio-fouling and it enhances the reliability of biosensor. The affordability of sensor to detect wide range molecules from small molecules to whole will create a common platform to overcome the current issues with naontheranostics. Nanobiosensors for Bio-molecular Targeting is a valuable reference resource that will help readers learn more about the latest analytical methods for detection of different substances in the range of small molecules to whole cells, exploring the advantages and disadvantages of each method. Explains the detection techniques used by nanosensors, exploring the strengths and weaknesses of each for the detection of diseaseShows how biosensors are used to detect various different types of biomoleculesDemonstrates how the use of nanomaterials makes biosensors both cheaper and more efficient INDICE: 1. Functionalization on biomolecules for efficient immobilization on sensing surfaces.2. Essentials in high-performance nanobiosensors3. Small molecular detection on sensor substrate4. Biosensor recognizes the receptor molecules5. Whole cell detection - an application for disease surveillance6. Nucleic acid complementation analysis on biosensor7. Analysis of glycan binding events on biosensor8. Determination of lipid components by biosensor9. Antibody-mediated diagnosis of biomolecules10. Aptamer-mediated diagnosis of biomolecules11. Biosensor assisted molecular discrimination12. Biosensor for the detection of cancer biomarkers13. Advancements of Nanobiosensor in Nanotheranostics

• ISBN: 978-0-12-813900-4
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 352
• Fecha Publicación: 01/09/2018
• Nº Volúmenes: 1
• Idioma: Inglés