Neural signaling: opportunities for novel diagnostic approaches and therapies

This volume describes a new international conference in the integrated field of neuromediators that has no predecessors and is set in a biomedical context of possible diagnostic and therapeutic approaches. Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. INDICE: Part I: New Biology of Cellular Receptors for Neuromediators: Regulation of Expression, Signal Transduction, and Mechanisms of Cross-talk:.1. G Protein-coupled Receptor Structures, Molecular Associations, and Modes of Regulation: Laurence J. Miller.2. Discovery of PACAP-regulated Genes through Microarray Analyses in Cell Culture and in Vivo: Lee E. Eiden, Babru Samal, MatthewJ. Gerdin, Tomris Mustafa, and Nikolas Stroth.3. Monitoring the State of Cholecystokinin Receptor Oligomerization after Ligand Binding Using Decay of Time-resolved Fluorescence Anisotropy: Kaleeckal G. Harikumar and Laurence J. Miller.4. Role of Pituitary Adenylate Cyclase Activating Polypeptide in the Pancreatic Endocrine System: Bo Ahrén.5. PTHrP Regulates Gli Transcriptional Activation: Lessons Learned from Bone Development and Cartilage Neoplasia: Benjamin A.Alman and Jay S. Wunder.6. Molecular Mechanisms of TRPV4-Mediated (neural) Signaling: Wolfgang Liedtke.7. The Sall2 Transcription Is a Novel p75NTR BindingProtein That Promotes the Development and Function of Neurons: Roxana Pincheira and David B. Donner.Part II: Neuromediator Participation in Host Defense, Immunity, and Inflammation:.8. Diverse Mechanisms and Consequences of Immunoadoption of Neuromediator Systems: Edward J. Goetzl, Robert C. Chan, Mahesh Yadav.9. Substance P in Stress and Anxiety: NK1 Receptor Antagonism Interacts with Key Brain Areas of the Stress Circuitry: Karl Ebner, Patrik Muigg, Georg Singewald, Nicolas Singewald.10. Mast Cells Stimulate Activated T Cells: Implications for Multiple Sclerosis: Theoharis C. Theoharides, Duraisamy Kempuraj, Taxiarchis Kourelis Akrivi Manola.11. VIP-mediated Th17 Differentiation: An Expanding Spectrum of VIP Effects in Immunity and Autoimmunity: Mahesh Yadav and Edward J. Goetzl.12. Neurokinin-1 Receptor Expression and Function Macrophages andBrain- Role in HIV Neuropathogenesis (Perspective): Steven D. Douglas, Jian-Ping Lai, Florin Tuluc, Lynnae Schwartz, and Laurie E. Kilpatrick.Part III: Neuromediators in Diseases:.13. Glutamate and Neurotrophic Factors in Neuronal Plasticity and Disease: Mark P. Mattson.14. Diversity of Neuropathogenic Mechanisms and Implications of Neuromediation of Diseases: Susan E Leeman.15. Inhibitory Effects of a Neurokinin-1 Receptor Antagonist on Postoperative Peritoneal Adhesion Formation: Karen L. Reed, Arthur F. Stucchi, Susan E. Leeman, and James M. Becker.16. Neuropeptides, Mesenteric Fat, and Intestinal Inflammation: Iordanes Karagiannides and Charalabos Pothoulakis.17. Gastrin-Releasing Peptide, Immune Responses, and Lung Disease: Simone Degan, Giselle Y. Lopez, and MaryE. Sunday.18. The VIP Gene Is a Key Modulator of Pulmonary Vascular Remodeling and Inflammation: Sami I. Said.Part IV: Neuromediators in Prenatal Development and Stress:.19. Prenatal Alcohol Exposure Increases Vulnerability to Stressand Anxiety-like Disorders in Adulthood: Kim G.C. Hellemans, Pamela Verma, Esther Yoon, Wayne Yu, and Joanne Weinberg.20. Role of Various Neurotransmittersin Mediating the Long-term Endocrine Consequences of Prenatal Alcohol Exposure: Soon Lee, Irene Choi, Sang Kang and Catherine Rivier.21. Perinatal MaternalFat Intake Affects Metabolism and Hippocampal Function in the Offspring: A Potential Role for Leptin: Claire-Dominique Walker, Lindsay Naef, Esterina dAsti, Hong Long, Zhifang Xu, Alain Moreau, and Bouziane Azeddine.Part V: Diagnostic and Therapeutic Strategies for Neuromediators in Diseases:.22. Informed Development of Drugs Acting at Family B G Protein-coupled Receptors: Laurence J. Miller.23. Experimental Therapeutic Strategies for Severe Sepsis: Mediators andMechanisms: William R. Parrish, Margot Gallowitsch-Puerta, Christopher J. Czura, and Kevin J. Tracey.24. A New Hypothesis: Activation of the Pro-opiomelanocortin Gene with Ketoconazole as a Treatment for Parkinsons Disease: Alberto Halabe Bucay.25. Opportunities and Challenges in the Discovery of New Central Nervous System Drugs: James E. Krause and Bertrand L. Chenard.26. Molecular Imaging to Biomarker Development in Neuroscience: J. James Frost.27. Studying theBrain Gut Axis with Pharmacological Imaging: Kirsten Tillisch, Zhuo Wang, Lisa Kilpatrick, Daniel P. Holschneider, and Emeran A. Mayer.Index of Contributors

• ISBN: 978-1-57331-704-7
• Editorial: New York Academy of Science
• Encuadernacion: Rústica
• Páginas: 360
• Fecha Publicación: 13/02/2009
• Nº Volúmenes: 1
• Idioma: Inglés