This book describes these exciting new developments, and presents experimental and computational findings that altogether describe the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. The book is written for bioengineers with interest in cellular mechanics, for biophysicists, biochemists, medical researchers and all other professionals with interest in how cells produce and respond to mechanicalloads. Shows new insights how cells produce and respond to mechanical loads. Provides a better understanding of the mechanical function of cells, and its relevance to their biological function. Describes the frontier of knowledge in cellular and biomolecular mechanics, and the biological implications, in health and disease. INDICE: Finite element modeling of cellular mechanics experiments. Multiscale computation of cytoskeletal mechanics during blebbing. Mechanobiology and finite element analysis of cellular injury during microbubble flows. Mathematical modeling of cell adhesion in tissue engineering using continuum models. Cell-material communication: mechanosensing modelling for design in tissue engineering. Mechanobiology in cancer. Structure-mechanical property changes in nucleus arising from breast cancer. Adhesion and signaling of tumor cells to leukocytes and endothelium in cancer metastasis. Cellular mechanics of acute leukemia and chemotherapy.
- ISBN: 978-3-642-14217-8
- Editorial: Springer Berlin Heidelberg
- Encuadernacion: Cartoné
- Páginas: 560
- Fecha Publicación: 01/02/2011
- Nº Volúmenes: 1
- Idioma: Inglés