Biomechanics of the Aorta: Modelling for Patient Care

Biomechanics of the Aorta: Modelling for Patient Care is a holistic analysis of the aorta towards its biomechanical description. This book addresses topics such as physiology, clinical imaging, tissue and blood flow modelling, knowledge that is then needed in diagnostics, aortic rupture prediction, assist surgical planning, and more. It encompasses a wide range of topics from basic sciences (Vascular biology, Continuum mechanics, Image analysis) to clinical applications, as well as describe and present computational studies and experimental benches, to mimic, understand and propose the best treatment of aortic pathologies. Divided into 5 parts, the book begins with introducing the fundamental aspects of the anatomy, biology, and physiopathology of the aorta, and proceeds to present the main computational fluid dynamic studies and biomechanical and mechanobiological models developed over the last decade. With approaches, methodologies and findings from contributors all over the world, this new volume of the Biomechanics of Living Organs series will increase understanding of aortic function as well as improve the design of medical devices and clinical interventions, including surgical procedures. Represents a comprehensive means for those involved in the aortic research and the related developments in the industry Introduces the most recent imaging technologies to characterize factors, such as aortic geometry, mechanical properties of the aortic tissue, and the local cellular activity in the vessel wall Synthesizes advances in vascular biomechanics, medical imaging, and computational finite element fluid and solid models to increase understanding of aorta function INDICE: Part 1 Anatomy, Biology, Physiopathology 1. Physiopathology 2. Genetics and aortic mechanisms 3. Patho-Physiology and mechanobiology of the aortic valve 4. Mechanobiology of aortic cells 5. Clinical treatment options Part 2 Imaging and tissue/rheology characterization 6. Rheology of aortic tissue - novel methods 7. Imaging aortic flows - 4DMRI 8. US imaging for aortic biomechanics 9. Functional imaging FDG PET 10. Image processing - deep learning for model reconstruction Part 3 Tissue modelling and rupture 11. Aortic valves modelling 12. AAA and thrombus modelling 13. Aneurysm growth mechanical and biology coupled 14. Rupture modelling - novel approaches 15. Multiscale modeling from protein to aortic tissue Part 4 Flow modelling and algorithm 16. Multiphysics flow modeling in the aorta 17. Novel approaches in FSI for the aorta 18. Turbulence modeling of blood flow 19. Inverse problems in aortic flow modelling 20. Modeling of Flow induced mechanosignaling 21. Reduced order modeling Part 5 Applications 22. TAVI aortic valve 23. AAA rupture prediction 24. (T)EVAR simulation 25. FSI in aortic dissections 26. Biomechanics of drug treatment 27. Artificial Intelligence-based approaches

• ISBN: 978-0-323-95484-6
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 450
• Fecha Publicación: 01/08/2023
• Nº Volúmenes: 1
• Idioma: Inglés