Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates

Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain. Provides an overview of brain targeting drug delivery that is useful to both academic and industry-based researchersDiscusses key points in developing brain targeting drug delivery systemsSummarizes and presents currently available strategies for brain targeting drug deliveryCovers not only current studies and their strengths, but also gives insight into the pitfalls of current research INDICE: 1. Introduction Part I Physiology and Principles for brain targeting drug delivery 2. Anatomy and physiology of the blood brain barrier 3. Blood brain barrier in CNS disorders 4. Recent progress in blood brain barrier and blood-CSF barrier transportation research Part II Brain targeting delivery strategies 5. Receptor mediated transportation through BBB 6. Carrier mediated transportation through BBB 7. Adsorptive mediated transportation through BBB 8. Physically open BBB 9. Intranasal drug delivery Part III Brain targeting delivery for CNS disorder management 10. Brain tumor targeting delivery systems 11. Brain targeting delivery systems for Alzheimer disease management 12. Brain targeting delivery systems for Parkinson's disease management 13. Brain targeting delivery systems for stroke management Part IV Perspective and pitfalls of brain targeting delivery 14. Neurotoxicity concern about the brain targeting delivery systems 15. The intra-brain distribution of brain targeting delivery systems 16. The excretion of brain targeting delivery systems 17. Perspective on brain targeting delivery systems

• ISBN: 978-0-12-814001-7
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 512
• Fecha Publicación: 01/10/2018
• Nº Volúmenes: 1
• Idioma: Inglés