Introduction to statistics in pharmaceutical clinical trials
Durham, Todd A.
Turner, J.Rick
Introduction to Statistics in Pharmaceutical Clinical Trials is an ideal introduction to statistics presented in the context of clinical trials conducted during pharmaceutical drug development. This novel approach both teaches the computational steps needed to conduct analyses and provides a conceptual understanding of how these analyses provide information that forms the rational basisfor decision making throughout the drug development process. INDICE: 1. The Discipline of Statistics: Introduction and Terminology: 2. The Role of Clinical Trials in New Drug Development: 3. Research Questions andResearch Hypotheses: 4. Study Design and Experimental Methodology: 5. Data, Central Tendency and Variation: 6. Probability, Hypothesis Testing and Estimation: 7. Early-phase Clinical Trials: 8. Confirmatory Clinical Trials: Safety Data I: 9. Confirmatory Clinical Trials: Safety Data II: 10. Confirmatory Trials: Analysis of Categorical Efficacy Data: 11. Confirmatory Clinical Trials of Analysis of Continuous Efficacy Data: 12. Additional Statistical Considerationsin Clinical Trials: 13. Concluding Comments: Appendix: References
- ISBN: 978-0-85369-714-5
- Editorial: Pharmaceutical Press
- Encuadernacion: Rústica
- Páginas: 240
- Fecha Publicación: 01/03/2008
- Nº Volúmenes: 1
- Idioma: Inglés