Long Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects

Long Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects offers a comprehensive overview of the technical, clinical, regulatory and industrial perspectives on these drug delivery systems. Implantable and long acting drug delivery systems are systems that offer the possibility of unattended and localized long lasting therapies. Accordingly, they offer multiple advantages over conventional drug delivery systems, such as improving patient compliance while reducing the required drug dosage, which is especially important for the treatment of chronic conditions. Long Acting Drug Delivery Systems: Pharmaceutical, Clinical, and Regulatory Aspects follows a sequential order, beginning with the current technical state of the field and moving on to more clinical, industrial and regulatory topics. Opening chapters describe the current needs and potential applications of implantable and long acting therapeutic approaches. The book goes on to describe established and novel long acting systems, with a focus on the materials used to prepare these systems and their biocompatibility. Importantly, applied topics such as scale-up manufacturing, products under clinical trials and regulatory aspects are covered, offering the reader a holistic view of this rapidly growing field. Brings together technical, clinical, regulatory and industrial perspectives, for a complete overview of long acting and implantable drug delivery systemsProvides up-to-date coverage of established and novel long acting and implantable drug delivery systems, both in development and actively in useAppeals to a broad readership, including materials scientists, pharmaceutical scientists, biomedical engineers, clinicians and regulatory experts INDICE: Part 1. Introduction to long acting and implantable drug delivery systems 1. Overview of the clinical current needs, potential applications and physiological consideration for long-acting and implantable delivery systems   Part 2. Classification, material types, and design principles of long acting drug delivery systems 2. Classification, material types and design approaches of long acting and implantable drug delivery systems Part 3. Applications of long acting drug delivery systems 3. Long acting drug delivery systems for ocular therapies 4. Applications of long lasting and implantable drug delivery systems for cardiovascular disease treatment 5. Implantable and long lasting drug delivery systems for cancer treatment 6. Sexual and reproductive health long lasting drug delivery systems applications 7. Implantable devices for pain control 8. Implantable and long lasting drug delivery systems for infectious, inflammatory, endocrine and neurodegenerative diseases 9. Long lasting drug delivery systems based on microneedles   Part 4. Safety issues and measures for long acting drug delivery systems 10. Safety and biocompatibility consideration of long acting and implantable drug delivery systems 11. Testing methodologies to evaluate safety of long acting and implantable drug delivery systems   Part 5. Industrial and regulatory aspects of long acting drug delivery systems 12. Scale-up manufacturing of long acting drug delivery systems. Products in the market and under clinical development 13. Regulatory aspects of long acting and implantable drug delivery systems. Challenges for clinical translation

• ISBN: 978-0-12-821749-8
• Editorial: Woodhead Publishing
• Encuadernacion: Rústica
• Páginas: 365
• Fecha Publicación: 01/07/2021
• Nº Volúmenes: 1
• Idioma: Inglés