Published continuously since 1944, the Advances in Protein Chemistry and Structural Biology serial has been a continuous, essential resource for protein chemists. Covering reviews of methodology and research in all aspects of protein chemistry, including purification/expression, proteomics, modeling and structural determination and design, each volume brings forth new information about protocols and analysis of proteins while presenting the most recent findings from leading experts in a broad range of protein-related topics. Covering various aspects such as their structure, function, regulation, and roles in cellular processesCovers subclasses of nuclear proteins, discussing their specific functions and involvement in different cellular processes such as DNA replication, transcription, DNA repair, and chromatin remodelingCovers signaling pathways and biochemical processes involved in their activation, transport, and localization within the nucleus INDICE: 1. Therapeutic insight into the role of nuclear protein HNF4a in liver carcinogenesisRamanathan Gnanasambandan Sr.2. Structural Mechanism of Nucleoporins in Cancer DiseaseSelvaraj Chandrabose Sr.3. Identification of nuclear matrix proteins (novel genes) in bladder cancer using Bioinformatic approachesGeorge Priya Doss C4. A comparative study of nuclear proteins of different cancers - A systematic reviewGeorge Priya Doss C5. Role of Lamins in Cellular Physiology and CancerAjaz Ahmad Bhat6. Pushing the envelope - how the genome interacts with the nuclear envelope in health and diseaseJoanna Bridger7. Identification of mutations and function analysis of nuclear proteins using bioinformatic approachesGeorge Priya Doss C8. uclear Hormone Receptors as Drug Targets: Advancements and Future ProspectsDileep Francis9. Proteins binding to tandemly repeated DNA: familiar strangersOlga Podgornaya and Natella Enukashvily10. HMGB1Iva Ugrinova11. R-loops and genome stabilityAnastas Gospodinov12. TBCVikas Rishi13. TBCPedro A Lazo14. Nuclear Tau accumulation in Alzheimer's DiseaseSubashchandrabose Chinnathambi15. Histone Deacetylase's (HDACs) regulates Tau function in Alzheimer's DiseaseSubashchandrabose Chinnathambi
- ISBN: 978-0-443-29564-5
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 488
- Fecha Publicación: 01/01/2025
- Nº Volúmenes: 1
- Idioma: Inglés