Intracellular Signalling Proteins, Volume 116 presents an overview of the current developments in mechanisms of intracellular signaling and involvement of these mechanisms in the development of a number of disorders and diseases. Opportunities for targeting the intracellular signaling cascades for benefiting patients are also discussed, along with chapters that focus on Voices from the Dead: The Complex Language of Dead Cells, Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology, Estrogen Receptor Signaling Mechanisms, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells: Regulation Cell Differentiation and Survival, and more. Describes advances in the discovery and application of therapeutics that target intracellular signaling mechanismsTargeted to a very wide audience of specialists, researchers and studentsContains timely chapters written by well-renowned authorities in their fieldIncludes a number of high quality illustrations, figures and tables INDICE: 1. Voices from the Dead: The Complex Language of Dead Cells Jerrold S Levine 2. Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology Suraj Unniappan 3. Estrogen receptor signaling mechanisms Patricia Silveyra 4. Intracellular signaling of the AMP-activating protein kinase Mentor Sopjani 5. Relationship between mitofusin 2 and cancer Alessandro Allegra 6. Molecular signaling in bone cells: regulation cell differentiation and survival Lilian Irene Plotkin 7. Activating mutations of the gp130/JAK/STAT pathway in human diseases Christoph Garbers 8. The role of aquaporins in inflammation Margherita Sisto 9. Intracellular signal transduction cascades in presynaptic neurons Jaewon Ko 10. Dopamine signaling in the striatum Emmanuel Valjent 11. Recent advances in computational studies of GPCR-G protein interactions Yinglong Miao 12. Cell signaling by fragile X family proteins Jean Martin Beaulieu
- ISBN: 978-0-12-815561-5
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 488
- Fecha Publicación: 01/05/2019
- Nº Volúmenes: 1
- Idioma: Inglés