Biophysical Approaches for the Study of Membrane Structure Part B

Biophysical Approaches for the Study of Membrane Structure, Part B, Volume 701 explores lipid membrane asymmetry and lateral heterogeneity. A burst of recent research has shown that bilayers whose leaflets differ in their physical properties-such as composition, phase state, or lateral stress-exhibit many fascinating new characteristics, but also pose a host of challenges related to their creation, characterization, simulation, and theoretical description. Chapters in this new release include Characterization of domain formation in complex membranes: Analyzing the bending modulus from simulations of complex membranes, The density-threshold affinity: Calculating lipid binding affinities from unbiased Coarse-Grain Molecular Dynamics simulations, and much more.Additional sections cover Uncertainty quantification for trans-membrane stresses and moments from simulation, Using molecular dynamics simulations to generate small-angle scattering curves and cryo-EM images of proteoliposomes, Binary Bilayer Simulations for Partitioning Within Membranes, Modeling Asymmetric Cell Membranes at All-atom Resolution, Multiscale remodeling of biomembranes and vesicles, Building complex membranes with Martini 3, Predicting lipid sorting in curved bilayer membranes, Simulating asymmetric membranes using P21 periodic boundary conditions, and many other interesting topics. Explore the state-of-the-art of lipid membrane asymmetryCovers experimental, theoretical, and computational techniques to create and characterize asymmetric lipid membranesTeaches how these kinds of approaches create and characterize laterally inhomogeneous membranes INDICE: 1. Characterization of domain formation in complex membranes: Analyzing the bending modulus from simulations of complex membranesRainer A. Böckmann2. The density-threshold affinity: Calculating lipid binding affinities from unbiased Coarse-Grain Molecular Dynamics simulationsGrace Brannigan, Jahmal Ennis, Ezry Santiago-McRae and Jesse W Sandberg3. Uncertainty quantification for trans-membrane stresses and moments from simulationMarkus Deserno4. Using molecular dynamics simulations to generate small-angle scattering curves and cryo-EM images of proteoliposomesMilka Doktorova5. Binary Bilayer Simulations for Partitioning Within MembranesWonpil Im, Richard Walter Pastor and Soohyung Park6. Modeling Asymmetric Cell Membranes at All-atom ResolutionJeffrey Klauda, Jessica Bodosa and Anthony Pane7. Multiscale remodeling of biomembranes and vesiclesReinhard Lipowsky8. Building complex membranes with Martini 3Siewert-Jan Marrink, Helgi Ingolfur Ingolfsson, Tugba Nur Ozturk, Melanie König, Timothy S. Carpenter, Kasper Busk Pedersen and Tsjerk A. Wassenaar9. Predicting lipid sorting in curved bilayer membranesLuca Monticelli, Cecile Hilpert and Jackson Crowley10. Simulating asymmetric membranes using P21 periodic boundary conditionsRichard Walter Pastor and Amy Rice11. Asymmetric Crowders and Membrane Morphology: A Multiscale Journey From Physical Chemistry to Oncology via BiophysicsRavi Radhakrishnan, Tobias Baumgart, Kshitiz Parihar, Seung-Hyun Ko, Wei Guo, Paul Janmey, Ryan Bradley, Phillip Taylor and Natesan Ramakrishnan12. Modeling the mechanochemical feedback for membrane-protein interactions using a continuum mesh modelPadmini Rangamani and Christopher Lee13. Lattice-based mesoscale simulations and mean-field theory of cell membrane adhesionBartosz Rózycki, Jingeli Hu, Long Li, Lukasz Milewski and Jie Gao14. Dynamic framework for large-scale modelling of membranes and peripheral proteinsMohsen Sadeghi and David Rosenberger15. Computing the spontaneous curvature of dynamic lipid complexes in molecular dynamics simulationsAlexander Sodt16. Non-affine deformation analysis and 3D packing defects: A new way to probe membrane heterogeneity in molecular simulationsAnand Srivastava and Madhusmita Tripathy17. Analyzing curvature and lipid distributions in molecular dynamics simulations of complex membranesPeter Tieleman

• ISBN: 978-0-443-29566-9
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 412
• Fecha Publicación: 15/08/2024
• Nº Volúmenes: 1
• Idioma: Inglés