Principles of Nutrigenetics and Nutrigenomics: Fundamentals of Individualized Nutrition
De Caterina, Raffaele
Martínez Cuevas, Alfredo J.
Kohlmeier, Martin
Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is the most comprehensive foundational text on the complex topics of nutrigenetics and nutrigenomics. Edited by three leaders in the field with contributions from researchers around the world, the book covers how the genetic make-up influences the response to foods and nutrients and how nutrients affect gene expression. This book is broken into four parts providing a valuable overview of genetics, nutrigenetics, and nutrigenomics, and a conclusion that will help translate research into practice. With an overview of the background, evidence, challenges, and opportunities in the field, readers will come away with a strong understanding of how this new science is the frontier of medical nutrition. Principles of Nutrigenetics and Nutrigenomics: Fundamentals for Individualized Nutrition is a valuable reference for students and researchers studying nutrition, genetics, medicine, and related fields. Provides a uniquely foundational, comprehensive, and systematic approach with full evidence-based coverage of established and emerging topics in nutrigenetics and nutrigenomicsIncludes a valuable guide to ethics for genetic testing for nutritional adviceProvides definitions, methods, summaries, figures, and tables to help students, researchers, and faculty grasp key concepts in each chapterWorks together with a companion website that includes slide decks, images, questions, and other teaching and learning aids designed to facilitate communication and comprehension of the content presented in the book INDICE: Section 1: The Biological Basis of Heritability and Diversity 1. The nature of traits, genes and variation 2. Epigenetic Mechanisms 3. Genotyping and sequencing 4. RNA analyses 5. Proteomic analyses 6. Metabolomic analyses 7. Epigenetics Methodology 8. Metagenomics 9. The role of nutrition in DNA damage and DNA repair 10. Study design in genetic epidemiology 11. Analytical methods in genetic epidemiology 12. Epistemology of nutrigenetic knowledge 13. Molecular biology of genetic variants Section 2: Nutrigenetics 14. Genomics of Eating Behavior and Appetite Regulation 15. (14 BIS) Control of food intake and physiologic functions by food tastants through ectopic taste receptors 16. Energy 17. Carbohydrates 18. Protein metabolism 19. Amino Acids - Inborn Errors / Amino Acids - Polymorphic Variations in Metabolism 20. Monounsaturated and Saturated Fatty Acids 21. Omega-3 and omega-6 fatty acids 22. Cholesterol and plant sterols 23. Phytanic acid 24. Alcohol 25. Vitamin A and other carotenoids 26. Vitamin D 27. Vitamin E 28. Vitamin K 29. Vitamin C 30. Vitamin B2 (Riboflavin) 31. Niacin 32. Folate, vitamin B6, B12 33. Biotin and pantothenate 34. Choline 35. Electrolytes 36. Iron 37. Trace elements 38. Polyphenols 39. Caffeine 40. Epigenetics in food allergies: the missing piece of the puzzle 41. Genetic variations impacting the response to defined diets 42. Genetic variations in the response to weight-loss diets 43. Perinatal nutrition 44. Gut microbiota and their influence on the response to foods 45. Aging 46. Body composition, obesity and anorexia 47. Genetic variations in the response to exercise: impact on physical fitness and performance 48. Cognitive function 49. Hyperuricemia and gout 50. Cardiovascular disease 51. Hemostasis and thrombosi 52. Diabetes mellitus 53. Nutrigenetics of Cancer 54. Bone health 55. Psychiatric diseases 56. Genetics of Chrononutrition 57. Genetics of impact on immunocompetence 58. Nutrigenetics and the liver Section 3: Nutrigenomics 59. Regulation of Gene Expression 60. Nutrients and gene expression in Obesity 61. Nutrients and gene expressio in Diabetes 62. Gene expression in dyslipemias 63. Nutrients and gene expression in Inflammation 64. Nutrients and gene expression in Cardiovascular Disease 65. Nutrients and Gene Expression in Cancer 66. Nutrients and Gene Expression Affecting Bone Metabolism 67. Nutrients and gene expression in developmental (in embroyonic and fetal development) 68. Methods in Nutrigenomics 69. A broader view on Omics and Systems Biology Section 4: Traditional Nutrigentics and Nutrigenomics 70. When is the evidence sufficient for use in practice 71. Newborn Screening 72. Nutrigenetics-Based Intervention Studies 73. Genome-based nutrition guidance 74. Nutripharmacogentics 75. Food technology solutions 76. Setting genome-directed guidelines and algorithms 77. Direct-to-consumer services 78. Ethical considerations in nutrigenetics and nutrigenomics 79. Privacy risks and protective measures 80. Legal frameworks in different countries 81. Impact of Nutrigenetics and Nutrigenomics on Society 82. Vitamins as Cofactors for Energy Homeostatsis and its Genetic Control
- ISBN: 978-0-12-804572-5
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 736
- Fecha Publicación: 01/09/2019
- Nº Volúmenes: 1
- Idioma: Inglés