Dietary Polyphenols and Healthy Aging: From Basic Science to Translational Research

Dietary Polyphenols and Healthy Aging: From Basic Science to Translational Research provides a thorough overview of the role of dietary polyphenols as agents to reduce the functional decline associated with aging.Polyphenols have an ability to influence some of the common denominators of aging, such as telomere attrition, epigenetic alterations, and mitochondrial dysfunction. In addition, Dietary Polyphenols and Healthy Aging: From Basic Science to Translational Research discusses the clinical and epidemiological evidence that indicates the consumption of polyphenols may improve a number of health-related variables in older adults. This book will be a valuable resource for geriatricians, gerontologist and members of nutrition field who are interested in how polyphenols can help to extend the healthy period of life and delay the development of chronic diseases. Describes the impact of polyphenols on the cellular and molecular mechanisms underlying aging Includes clinical insights on polyphenols to apply them to the wide range of aging diseases Presents population studies supporting the preventive role of polyphenols against age-related pathologies INDICE: Part 1 Experimental studies 1. Dietary polyphenols: structure, occurrence and bioactivity 2. Polyphenols and hallmarks of aging: an overview 3. Polyphenols, gut microbiota, and aging diseases 4. Polyphenols as hormetins to modulate aging pathways 5. Polyphenols, caloric restriction mimetics and aging process 6. Lifespan and healthspan extension by polyphenols 7. Concluding Remarks Part 2 Clinical studies 8. Polyphenols, large-scale clinical trials, and aging diseases 9. Flavonoids, atherosclerosis, and cardiovascular disease 10. Polyphenols as neuroprotective agents against brain aging and cognitive impairment 11. Polyphenols and mental health in elderly 12. Polyphenols and frailty status: a focus on mobility performance 13. Polyphenols and type 2 diabetes 14. Polyphenols and cancer 15. Concluding Remarks Part 3 Epidemiological studies 16. Polyphenols intake and healthy aging diets: A population perspective 17. Polyphenol rich-diets and aging diseases: a focus on Mediterranean diet 18. Polyphenols and all-cause mortality: evidence from epidemiological studies 19. Polyphenols and aging diseases: the Moli-sani study 20. Polyphenols and centenarian populations 21. Polyphenols and menopause: a focus on isoflavones and lignans in population studies 22. Dietary polyphenols and age-related diseases: experimental, epidemiological and clinical trial evidence 23. Concluding Remarks

• ISBN: 978-0-323-95596-6
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 465
• Fecha Publicación: 01/10/2023
• Nº Volúmenes: 1
• Idioma: Inglés