This volume highlights the remarkable superfamily of molecular motors called myosins, which are involved in such diverse cellular functions as muscle contraction, intracellular transport, cell migration and cell division. The different myosin classes are compared and contrasted in the introductory chapter, as well as chapters on myosin structure; and biochemical and kinetic properties of myosins. Subsequent chapters are devoted to single classes of myosins and provide keen insight based on studies using in vitro and in vivo systems into how particular myosins are designed for their intracellular roles. This highly authoritative and comprehensive volume includes current information on myosin mutations, which are responsible for diseases such as cardiomyopathies, immunodeficiences and neurological disorders, as well as hearing and vision defects. Chapters are written by experts in the field. Represents a compilation of information regarding many different myosins. Comprehensive nature of chapters with introductory chapters that deal with all myosin classes and other chapters that focus on one class. Timely and up-to-date. Fully referenced; moreover, index allows easy use as reference book INDICE: List of contributors. Structural and functional diversity of the myosin family of actin-based molecular motors. Myosin structure . The myosin family: biochemical and kinetic properties. Myosin I. Myosin II: Sarcomeric myosins, the motors of contraction in cardiac and skeletal muscles. Smooth-muscle myosin II. Non-muscle myosin II. Class III Myosins. Myosin V. Myosin VI: a multifunctional motor protein. Myosin VII. Plant Myosins VIII, XI, and XIII. Class IX Myosins Negative Regulators of the small GTP-binding Protein Rho. Myosin X. Myosin XIV and other myosins in protists. Myosin XVa. Index.
- ISBN: 978-1-4020-6516-3
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 482
- Fecha Publicación: 01/01/2008
- Nº Volúmenes: 1
- Idioma: Inglés