Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. Most existing books on spinal cord MRI are intended for radiologists and focus on qualitative rather than quantitative techniques used in clinical routine, such as T1/T2/PD-weighted MRI. This work instead includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory's applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord. Chapters authored by international experts in the field of magnetic resonance spectroscopyContains cooking recipes?-examples of imaging parameters for each quantitative technique-designed to aid researchers and clinicians in using them in practiceIdeal for clinical settings INDICE: Foreword Preface Part 1: Quantitative Biomarkers in the Spinal Cord: What For? 1.1 Application of Spinal Cord Quantitative MRI to Patients with Neurological Diseases other than MS 1.2 Inflammatory Demyelinating Diseases of the Spinal Cord 1.3 Traumatic Spinal Cord Injury (SCI) Part 2: Physics of MRI 2.1 Array Coils 2.2 B0 Inhomogeneity and Shimming 2.3 Susceptibility Artifacts 2.4 Ultra-High Field Part 3: Imaging Spinal Cord Structure 3.1 Diffusion-Weighted Imaging 3.2 Q-Space Imaging 3.3 Model-Based Microstructure Imaging: A Future Perspective 3.4 Magnetization Transfer 3.5 T2 Relaxation 3.6 Atrophy Part 4: Imaging Spinal Cord Function 4.1 fMRI Using BOLD 4.2 fMRI Using SEEP 4.2 Physiological Noise Modeling 4.3 Mapping the Vasculature of the Spinal Cord Part 5: Spectroscopy 5.1 Single Voxel MR Spectroscopy in the Spinal Cord: Technical Challenges and Clinical Applications Annex: Anatomy of the Spinal Cord
- ISBN: 978-0-12-396973-6
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 330
- Fecha Publicación: 21/04/2014
- Nº Volúmenes: 1
- Idioma: Inglés