Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications

In the last several decades, stem cells have greatly impacted the scientific and lay communities, providing huge advances in the treatment of devastating human diseases, including myocardial infarction, diabetes, muscular dystrophy, cystic fibrosis, cirrhosis, and osteoporosis. Alongside debates of induced pluripotent stem cells and embryonic stem cells has been the discovery of adult stem cells in many different tissues. While these organ resident or progenitor stem cells offer prospects to contribute to tissue regeneration, they also present challenges because of the complexity of organ structures. Resident Stem Cells and Regenerative Therapy: Sources and Clinical Applications, Second Edition presents the main findings to date and the important factors to be considered when contemplating resident stem cells in regenerative therapies. Chapters on cardiac, brain, neural, liver, kidney, skeletal muscle, bone, pancreatic, skin, and lung resident stem cells will assist in defining the level of success that has been achieved and the direction for the road ahead. With contributions from leading laboratories, open questions related to resident stem cells and regenerative therapies will also be presented for debate. Highlights basic research in tissue specific stem cells, experiments with animal models and clinical trials that are transforming the field of regeneration Provides a clear understanding of endogenous stem cells, their role in current regenerative therapies, and prospects for future research Reports on the main-stream clinical approaches and in vivo experiments published in primary literature to help categorizes the advances in various aspects of regenerative therapy and illustrate opportunities for clinical applications INDICE: 1. Resident Stem Cells in Kidney Tissue2. Pancreatic Stem Cells3. Tissue Engineering and the Role of Biomaterial Scaffolds: The Evolution of Cardiac Tissue Engineering4. Resident Neural Stem Cells5. Resident Stem Cell in Skin6. Lung Resident Stem Cells7. Skeletal Resident Stem Cells8. Cardiac Stem Cells9. The Neural Crest and the Stem Cells of Neural Crest10. Liver Resident Stem Cell11. Telocytes and Stem Cells13. Endothelial Progenitors for tissue regeneration14. Induced Pluripotent Stem Cells as an alternative for tissue repair

• ISBN: 978-0-443-15289-4
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 350
• Fecha Publicación: 01/07/2023
• Nº Volúmenes: 1
• Idioma: Inglés