Stimulated Raman Scattering Microscopy: Techniques and Applications

Stimulated Raman Scattering Microscopy: Techniques and Applications describes innovations in instrumentation, data science, chemical probe development, and various applications enabled by a state-of-the-art stimulated Raman scattering (SRS) microscope. Beginning by introducing the history of SRS, this book is composed of seven parts in depth including instrumentation strategies that have pushed the physical limits of SRS microscopy, vibrational probes (which increased the SRS imaging functionality), data science methods, and recent efforts in miniaturization. This rapidly growing field needs a comprehensive resource that brings together the current knowledge on the topic, and this book does just that. Researchers who need to know the requirements for all aspects of the instrumentation as well as the requirements of different imaging applications (such as different types of biological tissue) will benefit enormously from the examples of successful demonstrations of SRS imaging in the book. Led by Editor-in-Chief Ji-Xin Cheng, a pioneer in coherent Raman scattering microscopy, the editorial team has brought together various experts on each aspect of SRS imaging from around the world to provide an authoritative guide to this increasingly important imaging technique. This book is a comprehensive reference for researchers, faculty, postdoctoral researchers, and engineers. Includes every aspect from theoretic reviews of SRS spectroscopy to innovations in instrumentation and current applications of SRS microscopy Provides copious visual elements that illustrate key information, such as SRS images of various biological samples and instrument diagrams and schematics Edited by leading experts of SRS microscopy, with each chapter written by experts in their given topics INDICE: Preface Sunney XiePart 1: Theory 1. Coherent Raman scattering processes2. Sensitivity and noise in SRS microscopy 3. Stimulated Raman Scattering: ensembles to single molecules Part 2: Advanced Instrumentation and Emerging Modalities 4. Hyperspectral SRS imaging via spectral focusing 5. Balanced detection SRS microscopy 6. Multiplex stimulated Raman Scattering microscopy via a tuned amplifier 7. Impulsive SRS microscopy 8. Multicolor SRS imaging with wavelength-tunable/switchable lasers 9. Pulse-shaping-based SRS spectral imaging and applications 10. Background-free stimulated Raman scattering imaging by manipulating photons in the spectral domain 11. Coherent Raman scattering microscopy for superresolution vibrational imaging: Principles, techniques, and implementations 12. Quantum-enhanced stimulated Raman scattering 13. Stimulated Raman excited fluorescence (SREF) microscopy: Combining the best of two worlds 14. Instrumentation and methodology for volumetric stimulated Raman scattering imaging 15. SRS flow and image cytometry 16. Widely and rapidly tunable fiber laser for high-speed multicolor SRS 17. Compact fiber lasers for stimulated Raman scattering microscopy 18. Synchronized time-lens source for coherent Raman scattering microscopy Part 3: Vibrational Probes 19. Spontaneous Raman and SERS microscopy for Raman tag imaging 20. Stimulated Raman scattering imaging with small vibrational probes 21. Supermultiplexed vibrational imaging: From probe development to biomedical application 22. Raman beads for bio-imaging 23. Plasmon-enhanced stimulated Raman scattering microscopy Part 4: Data Science 24. Converting hyperspectral SRS into chemical maps 25. Compressive Raman microspectroscopy 26. Denoise SRS images Part 5: Applications to Life Sciences and Materials Science 27. Use of SRS microscopy for imaging drugs 28. Isotope-probed SRS (ip-SRS) imaging of metabolic dynamics in living organisms 29. Rapid determination of antimicrobial susceptibility by SRS single-cell metabolic imaging 30. Stimulated Raman scattering imaging of cancer metabolism: New avenue to precision medicine 31. Biomedical applications of SRS microscopy in functional genetics and genomics 32. Stimulated Raman voltage imaging for quantitative mapping of membrane potential 33. Neurodegenerative disease by SRS microscopy 34. Applications of stimulated Raman scattering (SRS) microscopy in materials science 35. Resolving molecular orientation by polarization-sensitive stimulated Raman scattering microscopy Part 6: Miniaturization and Translation to Medicine 36. Stimulated Raman histology 37. Miniaturized handheld stimulated Raman scattering microscope 38. Intraoperative multimodal imaging

• ISBN: 978-0-323-85158-9
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 610
• Fecha Publicación: 08/12/2021
• Nº Volúmenes: 1
• Idioma: Inglés