In the past thirty years, significant advances have been made in the field ofreproductive biology in unlocking the molecular and biochemical events that regulate spermatogenesis in the mammalian testis. In “Molecular Mechanisms in Spermatogenesis” a collection of chapters has been included written by colleagues on the latest development in the field using genomic and proteomic approaches to study spermatogenesis, as well as different mechanisms and/or molecules including environmental toxicants and transcription factors that regulate and/or affect spermatogenesis. The book begins with a chapter that provides the basic concept of cellular regulation of spermatogenesis. A few chapters are alsodedicated to some of the latest findings on the Sertoli cell cytoskeleton andother molecules (e.g., proteases, adhesion proteins) that regulate spermatogenesis. These chapters contain thought-provoking discussions and concepts whichshall be welcomed by investigators in the field. INDICE: 1. Spermatogenesis And Cycle Of The Seminiferous Epithelium. 2. Testicular Development And Spermatogenesis: Harvesting The Postgenomics Bounty. 3. Estrogens And Spermatogenesis. 4. Selenium, A Key Element In Spermatogenesis And Male Fertility. 5. Extracellular Matrix And Its Role In Spermatogenesis.6. Inflammatory Networks In The Control Of Spermatogenesis: Chronic Inflammation In An Immunologically Privileged Tissue. 8. Proteases And Their Cognate Inhibitors Of The Serine And Metalloprotease Subclasses, In Testicular Physiology. 10. Nitric Oxide And Cyclic Nucleotides: Their Roles In Junction Dynamics And Spermatogenesis. 11. The Sertoli Cell Cytoskeleton. 12. Blood-Testis Barrier, Junctional And Transport Proteins And Spermatogenesis. 13. Cross-Talk Between Tight And Anchoring Junctions Lesson From The Testis. 14. The Role Of The Leydig Cell In Spermatogenic Function. Index.
- ISBN: 978-0-387-79990-2
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 290
- Fecha Publicación: 01/10/2008
- Nº Volúmenes: 1
- Idioma: Inglés