Cell Press Reviews: Stem Cells to Model and Treat Disease provides in-depth and up-to-date reviews on the myriad ways that stem cells are being used to better understand and treat human disease. This publication offers essays from leaders in the stem cell field on some of the most important questions being faced in clinics and research labs, including the safety and efficacy of stem cell treatments, the use of stem cells to regenerate organs, the use of reprogrammed stem cells to model and treat disease, and the use of stem cells in clinical applications such as HIV disease and stroke. Contributors to this compilation include many prominent researchers in the field, such as: . Shinya Yamanaka, recipient, 2012 Nobel Prize in Physiology or Medicine; Professor, Center for iPS Cell Research and Application, Kyoto University and Gladstone Institute of Cardiovascular Disease, San Francisco, CA; President, International Society for Stem Cell Research . George Q. Daley, Director, Stem Cell Transplantation Program at Children's Hospital Boston; Professor, Children's Hospital Boston and Harvard Medical School . Irving Weissman, Director, Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine Cell Press Reviews: Stem Cells to Model and Treat Disease offers accessible and timely insights into the future promise and existing challenges of stem cell research. This publication is part of the Cell Press Reviews series, which brings together topical review articles recently published in Cell Press journals, including the Trends in. series. These compilations are curated by Cell Press journal editors and offer comprehensive updates from leaders in the field on the most cutting-edge and important scientific questions. . Provides timely overviews on a wide range of stem cell applications. Offers insight from experts on the key opportunities and challenges facing the field. Features reviews on genetic, cellular, and molecular aspects of stem-cell-based applications. Includes articles originally published in Cell, Cell Stem Cell, Neuron, Trends in Molecular Medicine, and Trends in Biotechnology INDICE: 1) Stem cell therapies could change medicine... if they get the chance; Irving Weissman; Cell Stem Cell 2) Why is it taking so long to develop clinically competitive stem cell therapies for CNS disorders? Olle Lindvall; Cell Stem Cell 3) Assessing the safety of stem cell therapeutics; Chris E.P. Goldring, Paul A. Duffy, Nissim Benvenisty, Peter W. Andrews, Uri Ben-David, Rowena Eakins, Neil French, Neil A. Hanley, Lorna Kelly, Neil R. Kitteringham, Jens Kurth, Deborah Ladenheim, Hugh Laverty, James McBlane, Gopalan Narayanan, Sara Patel, Jens Reinhardt, Annamaria Rossi, Michaela Sharpe and B. Kevin Park; Cell Stem Cell 4) The promise and perils of stem cell therapeutics; George Q. Daley; Cell Stem Cell 5) Reprogramming cellular identity for regenerative medicine; Anne B.C. Cherry and George Q. Daley; Cell 6) Cardiac stem cell therapy and the promise of heart regeneration; Jessica C. Garbern and Richard T. Lee; Cell Stem Cell 7) Next-generation regenerative medicine: Organogenesis from stem cells in 3D culture; Yoshiki Sasai; Cell Stem Cell 8) Induced pluripotent stem cells: past, present, and future; Shinya Yamanaka; Cell Stem Cell 9) Remodeling neurodegeneration: Somatic cell reprogramming-based models of adult neurological disorders; Liang Qiang, Ryousuke Fujita and Asa Abeliovich; Neuron 10) Therapeutic translation of iPSCs for treating neurological disease; Diana X. Yu, Maria C. Marchetto and Fred H. Gage; Cell Stem Cell 11) Modeling human disease with pluripotent stem cells: From genome association to function; Florian T. Merkle and Kevin Eggan; Cell Stem Cell 12) How can human pluripotent stem cells help decipher and cure Huntington's disease? Anselme Perrier and Marc Peschanski; Cell Stem Cell 13) Integrating human pluripotent stem cells into drug development; Sandra J. Engle and Dinesh Puppala; Cell Stem Cell 14) Process engineering of human pluripotent stem cells for clinical application; Margarida Serra, Catarina Brito, Cláudia Correia and Paula M. Alves; Trends in Biotechnology 15) Mesenchymal stem cells: Therapeutic outlook for stroke; Osamu Honmou, Rie Onodera, Masanori Sasaki, Stephen G. Waxman and Jeffery D. Kocsis; Trends in Molecular Medicine 16) The potential of stem cells as an in vitro source of red blood cells for transfusion; Anna Rita Migliaccio, Carolyn Whitsett, Thalia Papayannopoulou and Michel Sadelain; Cell Stem Cell 17) Hematopoietic-stem-cell-based gene therapy for HIV disease; Hans-Peter Kiem, Keith R. Jerome, Steven G. Deeks and Joseph M. McCune; Cell Stem Cell 18) Stem cells in translation; Cell
- ISBN: 978-0-12-420191-0
- Editorial: AP Cell
- Encuadernacion: Rústica
- Páginas: 374
- Fecha Publicación: 16/12/2013
- Nº Volúmenes: 1
- Idioma: Inglés