Concentrating on the most important and useful methods, this book provides illustrative examples of drug and natural product syntheses for use in the users' own work. This novel approach distills the truly groundbreaking reactions needed by every synthetic organic chemist. INDICE: ALKYLATIONS Enolate Alkylations (Evans, Meyers, Myers) Amino Acid Synthesis (Williams, Evans, Myers, Beak, Hoppe) ALDOL ADDITIONS Diastereoselective, Chiral Auxiliaries (Evans, Heathcock, Thorton, Masamune, Oppolzer) Enantioselective Catalysis (Evans, Keck, Carreira, Yamamoto, Corey) ALLYL METAL ADDITIONS Diastereoselctive, Auxiliary, Reagent Control (Roush, Brown, Hoffman) Enantioselective, Catalytic (Keck) C=O ADDITIONS AND REDUCTIONS Diastereocontrol (Felkin-Anh, Chelation Control, Directed) Enantioselective (CBS, Noyori, Brown, Mikami, Seebach, Soai, Knochel) EPOXIDES, OLEFIN EPOXIDATION, EPOXIDE TRANSFORMATIONS Diastereocontrol (Peracids, Dioxirane, VO(Acac), Mo(CO)6 Enantioselective Catalysis (Sharpless, Jacobsen) DIHYDROXYLATION, AMINOHYDROXYLATION Diastereoselective (Kishi, Evans) Enantioselective Catalysis (Sharpless, Corey Extension) HYDROBORATION Diastereoselective (Still, Kishi, Evans) C=C REDUCTIONS AND ADDITIONS Diastereoselective (Halolactonization, Haloetherification, Directed Reductions, Conjugate Additions, Michael) Enantioselective Catalysis (Buchwald, Noyori, Hoveyda, Burk, Knowles) CYCLOADDITIONS, REARRANGEMENTS Diasteroselective Enantioselective C=N ADDITIONS ANDREDUCTIONS (ENDERS, BUCHWALD) CHIRAL ACETALS MACROCYCLIC STEREOCONTROL (STILL, SCHREIBER) OLEFINATIONS Modern Modifications of Horner Emmons, Wittig Olefin Metathesis Trisubstituted Olefin Synthsis
- ISBN: 978-3-527-32452-1
- Editorial: Verlag Chemie
- Encuadernacion: Cartoné
- Páginas: 450
- Fecha Publicación: 24/09/2008
- Nº Volúmenes: 1
- Idioma: Inglés