Microtubule stabilizing and destabilizing agents: synthetic, structural and mechanistic insights
Carlomagno, T.
This series presents critical reviews of the present position and future trends in modern chemical research Short and concise reports on chemistry, each written by the world renowned experts Still valid and useful after 5 or 10 years INDICE: From the contents Bernhard Pfeiffer, Christian N. Kuzniewski, Christoph Wullschleger, and Karl-Heinz Altmann: Macrolide-Based Microtubule-Stabilizing Agents – Chemistry and Structure-Activity Relationships.- Ian Paterson and Gordon J. Florence: The Chemical Synthesis of Discodermolide.- J. Fernando Díaz, José Manuel Andreu, and Jesús Jiménez-Barbero: The Interaction of Microtubules with Stabilizers Characterized at Biochemical and Structural Levels.- Víctor M. Sánchez-Pedregal, and Christian Griesinger: The Tubulin Binding Mode of MT Stabilizing and Destabilizing Agents studied by NMR.- James H. Nettles and Kenneth H. Downing: The Tubulin Binding Mode of Microtubule Stabilizing Agents Studied by Electron Crystallography.- Benoit Gigant, Anthony Cormier, Audrey Dorleans, Raimond B. G. Ravelli, Marcel Knossow: Microtubule-Destabilizing Agents: Structural and Mechanistic Insights from the Interaction of Colchicineand Vinblastine with Tubulin.
- ISBN: 978-3-540-69036-8
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 200
- Fecha Publicación: 01/11/2008
- Nº Volúmenes: 1
- Idioma: Inglés