Clinical nephrotoxins: renal injury from drugs and chemicals

Clinical Nephrotoxins: Renal Injury from Drugs and Chemicals, Third Edition is a comprehensive text on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The importance of the toxicity of drugsand other substances for the kidneys is increasingly recognized. The book consists of themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. In addition, the volume highlights specific types of drugs, such as anti-infectious agents and anti-inflammatory, cardiovascular and anti-cancer drugs. The last section deals with prevention and focuses on urinary biomarkers, pharmacological aspects and drug dosage in renal failure. In this third and completely revised edition, several new topics were added and additional figures and tables included. Premier reference on nephrotoxins Comprehensive INDICE: From the contents Clinical Relevance/Approach.- Drug Associated Acute Renal Failure in the Intensive Care Unit.- Renal Handling of Drug and Xenobiotics.- Pharmacovigilance.- Immunologically-Mediated Toxin-Induced Renal Disease.- Cellular Mechanisms of Nephrotoxicity.- Animal Models for the Assessment of Acute Renal Dysfunction and Injury.- Renal Cell Culture Models: Contribution to the Understanding of Nephrotoxic Mechanisms.- Aminoglycosides and Vancomycin.- Beta-Lactam Antibiotics.- Amphotericin B.- Sulfonamides, Sulfadiazine,Timethoprim-Sulfamethoxazole, Pentamidine, Pyrimethamine, Dapsone, Quinolones.- Antiviral Agents.- Analgesics and 5-Aminosalicylic Acid.- Non-Steroidal Anti-Inflammatory Drugs.- Gold Salts, D-Penicillamine and Allopurinal.- Angiotensin I Converting Enzyme Inhibitors and Angiotensin II Receptor Antagonists.- Diuretics.- Anticancer Drugs.- Anesthetic Agents.- Proton Pump Inhibitor-Associated Acute and Chronic Interstitial Nephritis.- Illicit Drug Abuse.

• ISBN: 978-0-387-84842-6
• Editorial: Springer
• Encuadernacion: Cartoné
• Páginas: 1010
• Fecha Publicación: 01/10/2008
• Nº Volúmenes: 1
• Idioma: Inglés