Green Synthetic Approaches for Biologically Relevant Heterocycles: Volume 1: Advanced Synthetic Techniques

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of additional new chapters on hot topics in the field. Volume 1 explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles, classified on the basis of ring-size and/or the presence of heteratoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. Fully revised and updated, Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product, and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesisIncludes new chapters on varied multicomponent reactions, alongside both traditional and novel approachesPresents information in an accessible style with an emphasis on sustainability INDICE: 1. Green synthetic approaches for biologically relevant heterocycles: Advanced synthetic techniques - an overview 2. Use of Ball Milling for the Synthesis of Biologically Active Heterocycles 3. High pressure cycloaddition reactions in the synthesis of biologically relevant heterocycles 4. Microwave-induced synthesis of heterocycles of medicinal interests 5. Multicomponent reactions under microwave irradiation: a green path to biologically important heterocycles 6. Application of microwave irradiation in the synthesis of P-heterocycles 7. Green approaches for synthesis and functionalization of indole-based heterocycles of biological relevance 8. Sustainable one-pot domino reactions to access significant heterocycles employing dithioesters and their derivatives 9. Solvent-free synthesis of biologically relevant heterocyclic skeletons 10. Photocatalytic Minisci reaction: A promising and eco-friendly route to functionalize heteroaromatics of biological interest 11. Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds 12. Advances on greener processes for triazole synthesis via azide-alkyne cycloaddition reactions 13. Green Chemistry of Imines in Heterocyclic Synthesis 14. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes 15. Multicomponent approach for the sustainable synthesis of lawsone based heterocycles 16. Sustainable synthesis of Meldrum's acid derived heterocycles via multicomponent reactions

• ISBN: 978-0-12-820586-0
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 600
• Fecha Publicación: 01/02/2021
• Nº Volúmenes: 1
• Idioma: Inglés