Biotechnology of Microbial Enzymes: Production, Biocatalysis, and Industrial Applications

Biotechnology of Microbial Enzymes: Production, Biocatalysis, and Industrial Applications, Second Edition provides a complete survey of the latest innovations on microbial enzymes, highlighting biotechnological advances in their production and purification along with information on successful applications as biocatalysts in several chemical and industrial processes under mild and green conditions. The application of recombinant DNA technology within industrial fermentation and the production of enzymes over the last three decades have produced a host of useful chemical and biochemical substances. The power of these technologies results in novel transformations, better enzymes, a wide variety of applications, and the unprecedented development of biocatalysts through the ongoing integration of molecular biology methodology, all of which is covered insightfully and in-depth within the book. This fully revised, second edition is fully updated to address the latest research developments and applications in the field, from microbial enzymes recently applied in drug discovery to penicillin biosynthetic enzymes and penicillin acylase, xylose reductase, and microbial enzymes used in anti-tubercular drug design. Across chapters, the use of microbial enzymes in sustainable development and production processes is fully considered, with recent successes and ongoing challenges highlighted. Explores advances in microbial enzymes from basic science through application in multiple industry sectors Includes up-to-date discussions of metabolic pathway engineering, metagenomic screening, microbial genomes, extremophiles, rational design, directed evolution, and more Provides a holistic approach to the research of microbial enzymes and their use in sustainable processes and innovation Features all new chapters discussing microbial enzyme classes of growing interest, as well as enzymes recently applied in drug discovery and other applications INDICE: 1. Useful Microbial Enzymes: An Introduction2. Production, Purification, and Application of Microbial Enzymes3. Solid State Fermentation for Production of Microbial Cellulases4. Hyperthermophilic Subtilisin-Like Proteases from Thermococcus kodakarensis 5. Enzymes from Basidiomycetes: Peculiar and Efficient Tools for Biotechnology 6. Microbial Production and Molecular Engineering of Industrial Enzymes: Challenges and Strategies7. Metagenomics and the Search for Industrial Enzymes8. The Pocket Manual of Directed Evolution: Tips and Tricks9. Insights into the Structure and Molecular Mechanisms of ß-Lactam Synthesizing Enzymes in Fungi10. The Cellulosome: A Supramolecular Assembly of Microbial Biomass-Degrading Enzymes11. Microbial Enzymes of Use in Industry12. Significance of Microbial Glucokinases13. Lipase-Catalyzed Organic Transformations: A Recent Update 14. Enzymatic Biocatalysis in Chemical Transformations: A Promising and Emerging Field in Green Chemistry Practice15. Microbial Enzymes for Glycoside Synthesis: Development of Sucrose Phosphorylase as a Test Case16. Industrial Applications of Multistep Enzyme Reactions17. Biocatalysis for Industrial Production of Active Pharmaceutical Ingredients (APIs)18. Agro-Industrial Residues and Microbial Enzymes: An Overview on the Eco-Friendly Bioconversion into High Value-Added Products19. Microbial Enzymes for the Food Industry20. Productive Chain of Biofuels and Industrial Biocatalysis: Two Important Opportunities for Brazilian Sustainable Development21. Enzymes useful as drugs in human therapy 22. Molecular mechanisms of penicillin biosynthetic enzymes and penicillin acylases 23. Xylose reductase24. Mycobacterium tuberculosis dihydrodipicolinate synthase as target for anti-tubercular drug design

• ISBN: 978-0-443-19059-9
• Editorial: Academic Press
• Encuadernacion: Rústica
• Páginas: 672
• Fecha Publicación: 01/01/2023
• Nº Volúmenes: 1
• Idioma: Inglés