Spontaneous Pathology of the Laboratory Non-Human Primate

Pathologists often face a lack of suitable reference materials or historical data to determine if pathologic changes they are observing in monkeys are spontaneous or a consequence of other treatments or factors. By providing that background information, this text solves that problem. This book serves as a go to text for all pathologists working on primates in safety assessment studies, and to help diagnostic veterinary pathologists rule out spontaneous non-clinical disease pathology when assigning cause of death to these species in zoological collections. Primate species included are rhesus and cynomolgus macaques, and marmosets. Multi-authored chapters are arranged by organ system. Comprehensive text that describes the spontaneous pathology seen in the common laboratory primate species: rhesus and cynomolgus macaques, and marmosetsColor illustrations depict the most common lesions to augment the descriptionsDescriptions are compliant with the International Harmonization of Nomenclature and Diagnostic Criteria (INHAND) guidelines set forth by the Society of Toxicologic Pathology (STP), and currently utilized in rodent manuscripts published in the Japanese Journal of Toxicological Pathology and the Journal of Toxicologic PathologyProvides pathologists with common terms that are compliant with the FDA's Standard for Exchange of Nonclinical Data (SEND) guidelines INDICE: 1. Introduction to 1st Edition 2. Choice of Primate species 3. Regulatory issues in the use of primates 4. Infectious Diseases 5. Clinical Examination 6. Salivary glands 7. Oral Cavity 8. Esophagus and Stomach 9. Small and Large Intestine 10. Liver 11. Exocrine Pancreas 12. Kidney 13. Urinary bladder, ureter, urethra 14. Brain 15. Spinal Cord and Nerves 16. Eye and associated glands 17. Skeletal Muscle 18. Bone and Joints 19. Skin and subcutis 20. Specialized sebaceous glands 21. Mammary Gland 22. Respiratory tract 23. Immune System 24. Bone Marrow 25. Female Reproductive Tract 26. Testis 27. Male sex glands 28. Heart 29. Blood Vessels 30. Thyroid 31. Parathyroid 32. Pituitary 33. Adrenal 34. Endocrine Pancreas 35. Hematology

• ISBN: 978-0-12-813088-9
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 575
• Fecha Publicación: 01/06/2019
• Nº Volúmenes: 1
• Idioma: Inglés